New chiral derivatizing agents: Convenient determination of absolute configurations of free amino acids By 1H NMR

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The chiral carbonate reagents 5 allow for the direct and unambiguous determination of the absolute configurations of a wide range of free amino acids using 1H NMR. By using a ~3:1 mixture of (S)-5 and (R)-5, absolute configurations of the corresponding carbamates are determined by only analyzing the nitrogen protons.

Original languageEnglish (US)
Pages (from-to)911-914
Number of pages4
JournalOrganic Letters
Volume11
Issue number4
DOIs
StatePublished - Feb 19 2009
Externally publishedYes

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Carbamates
Carbonates
amino acids
Protons
Nitrogen
Nuclear magnetic resonance
Amino Acids
nuclear magnetic resonance
configurations
reagents
carbonates
nitrogen
protons
Proton Magnetic Resonance Spectroscopy

All Science Journal Classification (ASJC) codes

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

New chiral derivatizing agents : Convenient determination of absolute configurations of free amino acids By 1H NMR. / Kurosu, Michio; Li, Kai.

In: Organic Letters, Vol. 11, No. 4, 19.02.2009, p. 911-914.

Research output: Contribution to journalArticle

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