New phenylpropanoids with cytotoxic activities from Drypetes hainanensis

Tingting Zhang, Caiyun Zhang, Weiwei Guan, Dan Zhao, Ni An, Feng Chen, Bei Li, Xiaopo Zhang

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Phytochemical investigation on Drypetes hainanensis has resulted in the isolation of three new phenylpropanoids, named drypetesins A-C (1-3). Their structures were elucidated by applying various spectroscopic techniques (NMR, UV, IR, MS, and CD). The antiproliferative activities of these compounds were evaluated in vitro against three cultured cancer cell lines. Those new isolates exhibited potent cytotoxic activities against human hepatoma (HepG2), human breast adenocarcinoma (MCF-7), and human lung carcinoma (A-549) cancer cell lines with IC50 value range 5.6-14.8 μM.

Original languageEnglish (US)
Pages (from-to)186-189
Number of pages4
JournalPhytochemistry Letters
Volume12
DOIs
StatePublished - Jun 1 2015

Fingerprint

phenylpropanoids
Cells
Cell Line
Phytochemicals
cell lines
Human Activities
Inhibitory Concentration 50
Hepatocellular Carcinoma
Cultured Cells
Neoplasms
Adenocarcinoma
Breast
Nuclear magnetic resonance
hepatoma
adenocarcinoma
Carcinoma
Lung
cultured cells
phytopharmaceuticals
breasts

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Agronomy and Crop Science
  • Plant Science

Cite this

Zhang, T., Zhang, C., Guan, W., Zhao, D., An, N., Chen, F., ... Zhang, X. (2015). New phenylpropanoids with cytotoxic activities from Drypetes hainanensis. Phytochemistry Letters, 12, 186-189. https://doi.org/10.1016/j.phytol.2015.03.016

New phenylpropanoids with cytotoxic activities from Drypetes hainanensis. / Zhang, Tingting; Zhang, Caiyun; Guan, Weiwei; Zhao, Dan; An, Ni; Chen, Feng; Li, Bei; Zhang, Xiaopo.

In: Phytochemistry Letters, Vol. 12, 01.06.2015, p. 186-189.

Research output: Contribution to journalArticle

Zhang, T, Zhang, C, Guan, W, Zhao, D, An, N, Chen, F, Li, B & Zhang, X 2015, 'New phenylpropanoids with cytotoxic activities from Drypetes hainanensis', Phytochemistry Letters, vol. 12, pp. 186-189. https://doi.org/10.1016/j.phytol.2015.03.016
Zhang, Tingting ; Zhang, Caiyun ; Guan, Weiwei ; Zhao, Dan ; An, Ni ; Chen, Feng ; Li, Bei ; Zhang, Xiaopo. / New phenylpropanoids with cytotoxic activities from Drypetes hainanensis. In: Phytochemistry Letters. 2015 ; Vol. 12. pp. 186-189.
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