New prospects for management and treatment of inoperable and recurrent skull base meningiomas

Mahlon Johnson, Burak Sade, Michael T. Milano, Joung H. Lee, Steven A. Toms

Research output: Contribution to journalReview article

23 Citations (Scopus)

Abstract

Skull base, including optic nerve, cavernous sinus, clival and foramen magnum tumors represent a major challenge for neurosurgeons and neuro-oncologists. Growth regulatory signaling pathways for these tumors are of increasing interest as potential targets for new chemotherapy. Those differentially activated in various grades of meningiomas are currently being identified as well. This article reviews some recent findings pathways that appear to regulate meningioma growth. Potential targets for novel therapies are also discussed.

Original languageEnglish (US)
Pages (from-to)109-122
Number of pages14
JournalJournal of Neuro-Oncology
Volume86
Issue number1
DOIs
StatePublished - Jan 1 2008

Fingerprint

Skull Base
Meningioma
Foramen Magnum
Cavernous Sinus
Optic Nerve
Growth
Neoplasms
Drug Therapy
Therapeutics
Neurosurgeons
Oncologists

All Science Journal Classification (ASJC) codes

  • Oncology
  • Neurology
  • Clinical Neurology
  • Cancer Research

Cite this

New prospects for management and treatment of inoperable and recurrent skull base meningiomas. / Johnson, Mahlon; Sade, Burak; Milano, Michael T.; Lee, Joung H.; Toms, Steven A.

In: Journal of Neuro-Oncology, Vol. 86, No. 1, 01.01.2008, p. 109-122.

Research output: Contribution to journalReview article

Johnson, Mahlon ; Sade, Burak ; Milano, Michael T. ; Lee, Joung H. ; Toms, Steven A. / New prospects for management and treatment of inoperable and recurrent skull base meningiomas. In: Journal of Neuro-Oncology. 2008 ; Vol. 86, No. 1. pp. 109-122.
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