Noble gases in pure lipid membranes

Francisco Sierra Valdez, J. C. Ruiz-Suárez

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The mechanism of how a noble gas modifies the excitability of nerve cells and how such excitability can be recovered under hyperbaric pressure remains unclear. Here we present a calorimetric study where the melting point depression of pure lipid membranes induced by noble gases and its recovery with a hydrostatic pressure is addressed. A correlation is found between the electric polarizability (α) of these gases and their effect on the melting transition of the membranes. These results concur with other findings to support the idea that general anesthesia only depends on the ability of a certain atom or molecule to increase the general disorder of the membrane.

Original languageEnglish (US)
Pages (from-to)3167-3172
Number of pages6
JournalJournal of Physical Chemistry B
Volume117
Issue number11
DOIs
StatePublished - Mar 21 2013

Fingerprint

Noble Gases
Membrane Lipids
Inert gases
lipids
rare gases
membranes
Membranes
Hydrostatic pressure
Neurons
anesthesia
Melting point
Melting
Gases
nerves
Recovery
hydrostatic pressure
Atoms
Molecules
melting points
recovery

All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Surfaces, Coatings and Films
  • Materials Chemistry

Cite this

Sierra Valdez, F., & Ruiz-Suárez, J. C. (2013). Noble gases in pure lipid membranes. Journal of Physical Chemistry B, 117(11), 3167-3172. https://doi.org/10.1021/jp400367t

Noble gases in pure lipid membranes. / Sierra Valdez, Francisco; Ruiz-Suárez, J. C.

In: Journal of Physical Chemistry B, Vol. 117, No. 11, 21.03.2013, p. 3167-3172.

Research output: Contribution to journalArticle

Sierra Valdez, F & Ruiz-Suárez, JC 2013, 'Noble gases in pure lipid membranes', Journal of Physical Chemistry B, vol. 117, no. 11, pp. 3167-3172. https://doi.org/10.1021/jp400367t
Sierra Valdez F, Ruiz-Suárez JC. Noble gases in pure lipid membranes. Journal of Physical Chemistry B. 2013 Mar 21;117(11):3167-3172. https://doi.org/10.1021/jp400367t
Sierra Valdez, Francisco ; Ruiz-Suárez, J. C. / Noble gases in pure lipid membranes. In: Journal of Physical Chemistry B. 2013 ; Vol. 117, No. 11. pp. 3167-3172.
@article{908d4a1ba35145bbac8f223c4dbfddc8,
title = "Noble gases in pure lipid membranes",
abstract = "The mechanism of how a noble gas modifies the excitability of nerve cells and how such excitability can be recovered under hyperbaric pressure remains unclear. Here we present a calorimetric study where the melting point depression of pure lipid membranes induced by noble gases and its recovery with a hydrostatic pressure is addressed. A correlation is found between the electric polarizability (α) of these gases and their effect on the melting transition of the membranes. These results concur with other findings to support the idea that general anesthesia only depends on the ability of a certain atom or molecule to increase the general disorder of the membrane.",
author = "{Sierra Valdez}, Francisco and Ruiz-Su{\'a}rez, {J. C.}",
year = "2013",
month = "3",
day = "21",
doi = "10.1021/jp400367t",
language = "English (US)",
volume = "117",
pages = "3167--3172",
journal = "Journal of Physical Chemistry B",
issn = "1520-6106",
number = "11",

}

TY - JOUR

T1 - Noble gases in pure lipid membranes

AU - Sierra Valdez, Francisco

AU - Ruiz-Suárez, J. C.

PY - 2013/3/21

Y1 - 2013/3/21

N2 - The mechanism of how a noble gas modifies the excitability of nerve cells and how such excitability can be recovered under hyperbaric pressure remains unclear. Here we present a calorimetric study where the melting point depression of pure lipid membranes induced by noble gases and its recovery with a hydrostatic pressure is addressed. A correlation is found between the electric polarizability (α) of these gases and their effect on the melting transition of the membranes. These results concur with other findings to support the idea that general anesthesia only depends on the ability of a certain atom or molecule to increase the general disorder of the membrane.

AB - The mechanism of how a noble gas modifies the excitability of nerve cells and how such excitability can be recovered under hyperbaric pressure remains unclear. Here we present a calorimetric study where the melting point depression of pure lipid membranes induced by noble gases and its recovery with a hydrostatic pressure is addressed. A correlation is found between the electric polarizability (α) of these gases and their effect on the melting transition of the membranes. These results concur with other findings to support the idea that general anesthesia only depends on the ability of a certain atom or molecule to increase the general disorder of the membrane.

UR - http://www.scopus.com/inward/record.url?scp=84875442459&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84875442459&partnerID=8YFLogxK

U2 - 10.1021/jp400367t

DO - 10.1021/jp400367t

M3 - Article

C2 - 23438308

AN - SCOPUS:84875442459

VL - 117

SP - 3167

EP - 3172

JO - Journal of Physical Chemistry B

JF - Journal of Physical Chemistry B

SN - 1520-6106

IS - 11

ER -