Normal organ standard uptake values in carbon-11 acetate PET imaging

Won S. Song, Brett R. Nielson, Kevin P. Banks, Yong Bradley

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objective The goal of this study was to determine normal standard uptake values of carbon-11 (1111C) acetate in healthy organs. By accurately determining the range of physiologic activity, abnormal focal or diffuse 11 11C-acetate activity can be more accurately assessed and thus improve the sensitivity and specificity of this emerging diagnostic PET agent Methods We reviewed all 55 patients (mean age±SD 64.8 ±10.8, age range 35-88 years) who underwent 1111C-acetate PET/computed tomography at our institution from 2005 to 2007. Regions of interest were drawn in organs that were devoid of clinical or imaging evidence of disease. The maximum standard uptake value for each region was calculated and analyzed for mean, standard deviation, and 95% confidence intervals. Results The results are presented as average maximum standard uptake value ±1 SD with the pancreas, liver, spleen and salivary glands showing the greatest 1111C-acetate avidity. A review of the literature shows our results to be similar to those published earlier.

Original languageEnglish (US)
Pages (from-to)462-465
Number of pages4
JournalNuclear Medicine Communications
Volume30
Issue number6
DOIs
StatePublished - Jun 1 2009

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Acetates
Salivary Glands
Pancreas
Spleen
Tomography
Confidence Intervals
Sensitivity and Specificity
Liver
carbon-11 acetate

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Normal organ standard uptake values in carbon-11 acetate PET imaging. / Song, Won S.; Nielson, Brett R.; Banks, Kevin P.; Bradley, Yong.

In: Nuclear Medicine Communications, Vol. 30, No. 6, 01.06.2009, p. 462-465.

Research output: Contribution to journalArticle

Song, Won S. ; Nielson, Brett R. ; Banks, Kevin P. ; Bradley, Yong. / Normal organ standard uptake values in carbon-11 acetate PET imaging. In: Nuclear Medicine Communications. 2009 ; Vol. 30, No. 6. pp. 462-465.
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