Obstructive sleep apnea during pregnancy resulting in pulmonary hypertension

David F. Lewis, Andrew L. Chesson, Michael S. Edwards, Jonathan W. Weeks, Charles Adair

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Obesity is known to increase maternal morbidity and mortality. We describe a case of obstructive sleep apnea due to obesity and discuss our treatment of the resulting pulmonary hypertension. A patient was transferred to our hospital at 29 weeks' gestation with severe anasarca and more than a 100-pound weight gain during pregnancy. Pulmonary hypertension due to obstructive sleep apnea was diagnosed. The patient was treated with nasal continuous positive airway pressure (CPAP) during sleep and remained in the hospital the remainder of her pregnancy. She had a massive spontaneous diuresis during her hospital stay and lost more than 100 pounds. She was delivered at term via cesarean section because of transverse lie. Preoperative hemodynamic monitoring confirmed the diagnosis of pulmonary hypertension. This represents the first case in the literature of obstructive sleep apnea leading to pulmonary hypertension in pregnancy. This patient responded well to nasal CPAP as evident by the massive diuresis and good maternal outcome.

Original languageEnglish (US)
Pages (from-to)761-762
Number of pages2
JournalSouthern Medical Journal
Volume91
Issue number8
DOIs
StatePublished - Jan 1 1998
Externally publishedYes

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Obstructive Sleep Apnea
Pulmonary Hypertension
Pregnancy
Continuous Positive Airway Pressure
Diuresis
Obesity
Maternal Mortality
Cesarean Section
Weight Gain
Length of Stay
Edema
Sleep
Hemodynamics
Mothers
Morbidity
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Obstructive sleep apnea during pregnancy resulting in pulmonary hypertension. / Lewis, David F.; Chesson, Andrew L.; Edwards, Michael S.; Weeks, Jonathan W.; Adair, Charles.

In: Southern Medical Journal, Vol. 91, No. 8, 01.01.1998, p. 761-762.

Research output: Contribution to journalArticle

Lewis, David F. ; Chesson, Andrew L. ; Edwards, Michael S. ; Weeks, Jonathan W. ; Adair, Charles. / Obstructive sleep apnea during pregnancy resulting in pulmonary hypertension. In: Southern Medical Journal. 1998 ; Vol. 91, No. 8. pp. 761-762.
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