Oligofructose provides laxation for irregularity associated with low fiber intake

Randal Buddington, Cavita Kapadia, Franka Neumer, Stephan Theis

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Inadequate dietary fiber intake contributes to the prevalent irregularity and constipation in Western countries. Although eating adequate amounts of fibers from fiber-rich foods, foods with added fibers and dietary fiber supplements is considered the first option for improving laxation, the efficacy can vary among types of fibers. The present study is a randomized control trial that included healthy adult participants with ≤3 bowel movements/week and a habitual low dietary fiber intake in a parallel design to evaluate the benefits for laxation by supplementing the daily diet with oligofructose (Orafti® P95; OF), a fermentable source of fiber and established prebiotic (n = 49); maltodextrin was the placebo (n = 48). After a run-in phase, OF was initially provided at 5 g/day, then increased to 10 and 15 g/day with four weeks for each phase. Stool frequency (bowel movements per week) for the OF and maltodextrin (MD) groups were initially similar (3.98 ± 1.49 vs. 4.06 ± 1.48), did not change for the placebo group, but increased for the OF group with the difference significant at 15 g/day (p = 0.023). Stool consistency was similar and remained unchanged at all doses for both groups. Gastrointestinal sensations were low for both groups. Laxation benefits were especially pronounced for participants with >13 g/day habitual dietary fiber intake, with significant laxation at 10 g and 15 g OF/day (p = 0.04 and p = 0.004, respectively) A daily supplement with a short-chain inulin-type fructan derived from chicory roots, i.e., oligofructose (Orafti® P95) provided a laxation effect without causing gastrointestinal (GI) distress for healthy participants with irregularity associated with low dietary fiber intake.

Original languageEnglish (US)
Article number1372
JournalNutrients
Volume9
Issue number12
DOIs
StatePublished - Dec 18 2017

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fructooligosaccharides
Dietary Fiber
dietary fiber
Healthy Volunteers
Chicory
Placebos
Fructans
Food
Prebiotics
Inulin
maltodextrins
Constipation
Dietary Supplements
placebos
Eating
oligofructose
Diet
constipation
chicory
fructans

All Science Journal Classification (ASJC) codes

  • Food Science
  • Nutrition and Dietetics

Cite this

Oligofructose provides laxation for irregularity associated with low fiber intake. / Buddington, Randal; Kapadia, Cavita; Neumer, Franka; Theis, Stephan.

In: Nutrients, Vol. 9, No. 12, 1372, 18.12.2017.

Research output: Contribution to journalArticle

Buddington, Randal ; Kapadia, Cavita ; Neumer, Franka ; Theis, Stephan. / Oligofructose provides laxation for irregularity associated with low fiber intake. In: Nutrients. 2017 ; Vol. 9, No. 12.
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