Omeprazole, a gastric 'proton pump inhibitor'

Lack of effect on renal handling of electrolytes and urinary acidification

Colin Howden, J. L. Reid

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Omeprazole has previously been shown to be a potent inhibitor of gastric acid secretion in man. In a new study, oral omeprazole 60 mg/day was given to 8 healthy male subjects for 8 days. The daily urinary electrolyte output and urine pH in response to ammonium chloride were not significantly altered. This provides further support for the specificity of its action on gastric acid secretion.

Original languageEnglish (US)
Pages (from-to)639-640
Number of pages2
JournalEuropean Journal of Clinical Pharmacology
Volume26
Issue number5
DOIs
StatePublished - Sep 1 1984
Externally publishedYes

Fingerprint

Omeprazole
Proton Pump Inhibitors
Gastric Acid
Electrolytes
Stomach
Kidney
Ammonium Chloride
Healthy Volunteers
Urine

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)

Cite this

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