Ontogenesis of glucose sensitivity in the rat lateral hypothalamus

a brain slice study.

S. Shibata, Y. Oomura, Hitoshi Kita

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The development of glucose-sensitive neurons in the lateral hypothalamus (LHA) brain slices was examined. In 60-100-day-old rats, 20% of LHA neurons were sensitive, that is, their firing rates decreased upon increase in the glucose concentration in the perfusate and increased upon decrease in glucose concentration. In 2-, 3- and 7-day-old rats, 16% of the neurons were glucose sensitive. Results confirm glucose-sensitivity in the LHA at a very early stage of ontogeny.

Original languageEnglish (US)
Pages (from-to)114-117
Number of pages4
JournalBrain Research
Volume281
Issue number1
StatePublished - Sep 1 1982
Externally publishedYes

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Lateral Hypothalamic Area
Glucose
Brain
Neurons

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Cite this

Ontogenesis of glucose sensitivity in the rat lateral hypothalamus : a brain slice study. / Shibata, S.; Oomura, Y.; Kita, Hitoshi.

In: Brain Research, Vol. 281, No. 1, 01.09.1982, p. 114-117.

Research output: Contribution to journalArticle

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