Oral manifestations of Wegener's granulomatosis

A report of three cases and a literature review

Carol Stewart, Donald Cohen, Indraneel Bhattacharyya, Lawrence Scheitler, Steven Riley, Kenneth Calamia, Cesar Migliorati, Ronald Baughman, Perry Langford, Joseph Katz

Research output: Contribution to journalReview article

61 Citations (Scopus)

Abstract

Background. Hyperplastic granular gingivitis or "strawberry gingivitis" is a rare manifestation of Wegener's granulomatosis (WG), but it is nearly pathognomonic for this multisystem autoimmune vasculitis. The dentist may be the first health care profes sional to see patients with symptoms and findings of this condition. Early diagnosis and treatment is the most important factor in the management of this potentially fatal disease. Methods. The authors present three case reports that demonstrate the disease spectrum and conducted a literature review focused on current understanding of this disease. Results. The first patient had only the classic gingival manifestations of the disease. The second patient had simultaneous typical gingival lesions, as well as dermatologic findings. The third patient had an atypical oral presentation of aphthous ulcers and erythematous gingiva, as well as respiratory and genital involvement. Reaching a definitive diagnosis sometimes is challenging owing to the subtle onset of the disease and variable clinical and laboratory findings. Conclusion and Clinical Implications. Clinicians should be familiar with the broad variety of oral and systemic components of WG, as well as strategies to facilitate prompt disease recognition and to provide continued oral health care to these medically complex patients.

Original languageEnglish (US)
Pages (from-to)338-348
Number of pages11
JournalJournal of the American Dental Association
Volume138
Issue number3
DOIs
StatePublished - Jan 1 2007

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Oral Manifestations
Granulomatosis with Polyangiitis
Gingivitis
Gingival Diseases
Aphthous Stomatitis
Delivery of Health Care
Fragaria
Oral Health
Gingiva
Vasculitis
Dentists
Early Diagnosis

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

Stewart, C., Cohen, D., Bhattacharyya, I., Scheitler, L., Riley, S., Calamia, K., ... Katz, J. (2007). Oral manifestations of Wegener's granulomatosis: A report of three cases and a literature review. Journal of the American Dental Association, 138(3), 338-348. https://doi.org/10.14219/jada.archive.2007.0166

Oral manifestations of Wegener's granulomatosis : A report of three cases and a literature review. / Stewart, Carol; Cohen, Donald; Bhattacharyya, Indraneel; Scheitler, Lawrence; Riley, Steven; Calamia, Kenneth; Migliorati, Cesar; Baughman, Ronald; Langford, Perry; Katz, Joseph.

In: Journal of the American Dental Association, Vol. 138, No. 3, 01.01.2007, p. 338-348.

Research output: Contribution to journalReview article

Stewart, C, Cohen, D, Bhattacharyya, I, Scheitler, L, Riley, S, Calamia, K, Migliorati, C, Baughman, R, Langford, P & Katz, J 2007, 'Oral manifestations of Wegener's granulomatosis: A report of three cases and a literature review', Journal of the American Dental Association, vol. 138, no. 3, pp. 338-348. https://doi.org/10.14219/jada.archive.2007.0166
Stewart, Carol ; Cohen, Donald ; Bhattacharyya, Indraneel ; Scheitler, Lawrence ; Riley, Steven ; Calamia, Kenneth ; Migliorati, Cesar ; Baughman, Ronald ; Langford, Perry ; Katz, Joseph. / Oral manifestations of Wegener's granulomatosis : A report of three cases and a literature review. In: Journal of the American Dental Association. 2007 ; Vol. 138, No. 3. pp. 338-348.
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