Orbital and eyelid manifestations of xanthogranulomatous diseases

Valerie L. Vick, Matthew Wilson, James Fleming, Barrett G. Haik

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Erdheim-Chester disease, adult periocular xanthogranuloma, juvenile xanthogranuloma, and necrobiotic xanthogranuloma are presumed to be separate disease entities, but they are often confused clinically because of their similar presentations and histopathology. To further describe the xanthogranulomatous diseases and to identify possible pitfalls in their diagnoses, we retrospectively reviewed charts from 1998 to 2001 for all patients with biopsy-proven xanthogranulomatous process of the eyelid and/or orbit. We found 2 patients diagnosed with adult periocular xanthogranuloma and 1 with Erdheim-Chester disease, each case initially misdiagnosed. Careful review of the clinical manifestations, histopathological review of all previous biopsy specimens, and repeat biopsy aided in the correct diagnosis and management of disease in these 3 patients.

Original languageEnglish (US)
Pages (from-to)221-225
Number of pages5
JournalOrbit
Volume25
Issue number3
DOIs
StatePublished - Sep 1 2006

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Eyelids
Erdheim-Chester Disease
Biopsy
Necrobiotic Xanthogranuloma
Juvenile Xanthogranuloma
Orbit
Disease Management
Diagnostic Errors

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

Orbital and eyelid manifestations of xanthogranulomatous diseases. / Vick, Valerie L.; Wilson, Matthew; Fleming, James; Haik, Barrett G.

In: Orbit, Vol. 25, No. 3, 01.09.2006, p. 221-225.

Research output: Contribution to journalArticle

Vick, Valerie L. ; Wilson, Matthew ; Fleming, James ; Haik, Barrett G. / Orbital and eyelid manifestations of xanthogranulomatous diseases. In: Orbit. 2006 ; Vol. 25, No. 3. pp. 221-225.
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