Orbital hyperostosis following exenteration

James Fleming, James S. Linder, Zeynel A. Karcioglu

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

PURPOSE: To report the development of unilateral, diffuse hyperostosis of orbital bones in 3 postexenteration patients. METHODS: Three advanced cases of periorbital and orbital malignancies are presented, and their clinical, radiologic, and histopathologic features are reviewed. RESULTS: Postexenteration CT showed thickened orbital walls in all 3 cases. The histopathology revealed necrotic destruction of the trabeculae mixed with randomly distributed chronic inflammatory cells and fibrosis and inflamed overlying granulation tissue. CONCLUSION: The delayed healing of the granulation tissue during secondary intention in these cases is quite likely the cause of chronic osteitis of the underlying orbital bone that, in turn, led to postoperative diffuse hyperostosis.

Original languageEnglish (US)
Pages (from-to)378-382
Number of pages5
JournalOphthalmic Plastic and Reconstructive Surgery
Volume24
Issue number5
DOIs
StatePublished - Sep 1 2008

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Hyperostosis
Granulation Tissue
Bone and Bones
Osteitis
Fibrosis
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery
  • Ophthalmology

Cite this

Orbital hyperostosis following exenteration. / Fleming, James; Linder, James S.; Karcioglu, Zeynel A.

In: Ophthalmic Plastic and Reconstructive Surgery, Vol. 24, No. 5, 01.09.2008, p. 378-382.

Research output: Contribution to journalReview article

Fleming, James ; Linder, James S. ; Karcioglu, Zeynel A. / Orbital hyperostosis following exenteration. In: Ophthalmic Plastic and Reconstructive Surgery. 2008 ; Vol. 24, No. 5. pp. 378-382.
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AB - PURPOSE: To report the development of unilateral, diffuse hyperostosis of orbital bones in 3 postexenteration patients. METHODS: Three advanced cases of periorbital and orbital malignancies are presented, and their clinical, radiologic, and histopathologic features are reviewed. RESULTS: Postexenteration CT showed thickened orbital walls in all 3 cases. The histopathology revealed necrotic destruction of the trabeculae mixed with randomly distributed chronic inflammatory cells and fibrosis and inflamed overlying granulation tissue. CONCLUSION: The delayed healing of the granulation tissue during secondary intention in these cases is quite likely the cause of chronic osteitis of the underlying orbital bone that, in turn, led to postoperative diffuse hyperostosis.

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