Panoramic and skull imaging may aid in the identification of multiple myeloma lesions

Karina Morais Faria, Thais Bianca Brandão, Wagner Gomes Silva, Juliana Pereira, Frederico Sam Paio Neves, Marcelo Corrêa Alves, Werner Shintaku, Marcio Ajudarte Lopes, Ana Carolina Prado Ribeiro, Cesar Augusto Migliorati, Alan Roger Santos-Silva

Research output: Contribution to journalArticle

Abstract

Background: The purpose of this study was to investigate the presence of punched-out lesions in craniofacial bones using three different radiographic protocols in a large cohort of patients. Material and Methods: One hundred fifty-five MM patients were evaluated using panoramic and skull (frontal and lateral) radiographs, which were performed in all patients at the time of MM diagnosis. The diagnostic potential for detecting punched-out lesions was compared among the radiographic techniques. Results: MM punched-out lesions were identified in 135 (87%) panoramic radiographs, 141 (91%) frontal and 144 (93%) lateral skull radiographs. Punched out-lesions were synchronously present in skull and jawbones in 129 (83.23 %) cases. The lesions were detected exclusively in skull in 18 (11.61%) cases and exclusively in jawbones in 6 (3.87%) cases. Punched out-lesion mainly affected the skull and the jawbones in a synchronous way (p<0.001) rather than separately. Conclusions: All investigated radiographic techniques (panoramic, frontal and lateral skull approaches) demonstrated high detection rates for MM punched-out lesions in craniofacial bones. Panoramic radiography may aid to the radiographic protocols to identify multiple myeloma bone lesions.

Original languageEnglish (US)
Article number22123
Pages (from-to)e38-e47
JournalMedicina Oral Patologia Oral y Cirugia Bucal
Volume23
Issue number1
DOIs
StatePublished - Jan 20 2018

Fingerprint

Multiple Myeloma
Skull
Bone and Bones
Panoramic Radiography

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology
  • Dentistry(all)

Cite this

Faria, K. M., Brandão, T. B., Silva, W. G., Pereira, J., Neves, F. S. P., Alves, M. C., ... Santos-Silva, A. R. (2018). Panoramic and skull imaging may aid in the identification of multiple myeloma lesions. Medicina Oral Patologia Oral y Cirugia Bucal, 23(1), e38-e47. [22123]. https://doi.org/10.4317/medoral.22123

Panoramic and skull imaging may aid in the identification of multiple myeloma lesions. / Faria, Karina Morais; Brandão, Thais Bianca; Silva, Wagner Gomes; Pereira, Juliana; Neves, Frederico Sam Paio; Alves, Marcelo Corrêa; Shintaku, Werner; Lopes, Marcio Ajudarte; Ribeiro, Ana Carolina Prado; Migliorati, Cesar Augusto; Santos-Silva, Alan Roger.

In: Medicina Oral Patologia Oral y Cirugia Bucal, Vol. 23, No. 1, 22123, 20.01.2018, p. e38-e47.

Research output: Contribution to journalArticle

Faria, KM, Brandão, TB, Silva, WG, Pereira, J, Neves, FSP, Alves, MC, Shintaku, W, Lopes, MA, Ribeiro, ACP, Migliorati, CA & Santos-Silva, AR 2018, 'Panoramic and skull imaging may aid in the identification of multiple myeloma lesions', Medicina Oral Patologia Oral y Cirugia Bucal, vol. 23, no. 1, 22123, pp. e38-e47. https://doi.org/10.4317/medoral.22123
Faria, Karina Morais ; Brandão, Thais Bianca ; Silva, Wagner Gomes ; Pereira, Juliana ; Neves, Frederico Sam Paio ; Alves, Marcelo Corrêa ; Shintaku, Werner ; Lopes, Marcio Ajudarte ; Ribeiro, Ana Carolina Prado ; Migliorati, Cesar Augusto ; Santos-Silva, Alan Roger. / Panoramic and skull imaging may aid in the identification of multiple myeloma lesions. In: Medicina Oral Patologia Oral y Cirugia Bucal. 2018 ; Vol. 23, No. 1. pp. e38-e47.
@article{7643d1cf8b1c42d9a152e2a89b0060d5,
title = "Panoramic and skull imaging may aid in the identification of multiple myeloma lesions",
abstract = "Background: The purpose of this study was to investigate the presence of punched-out lesions in craniofacial bones using three different radiographic protocols in a large cohort of patients. Material and Methods: One hundred fifty-five MM patients were evaluated using panoramic and skull (frontal and lateral) radiographs, which were performed in all patients at the time of MM diagnosis. The diagnostic potential for detecting punched-out lesions was compared among the radiographic techniques. Results: MM punched-out lesions were identified in 135 (87{\%}) panoramic radiographs, 141 (91{\%}) frontal and 144 (93{\%}) lateral skull radiographs. Punched out-lesions were synchronously present in skull and jawbones in 129 (83.23 {\%}) cases. The lesions were detected exclusively in skull in 18 (11.61{\%}) cases and exclusively in jawbones in 6 (3.87{\%}) cases. Punched out-lesion mainly affected the skull and the jawbones in a synchronous way (p<0.001) rather than separately. Conclusions: All investigated radiographic techniques (panoramic, frontal and lateral skull approaches) demonstrated high detection rates for MM punched-out lesions in craniofacial bones. Panoramic radiography may aid to the radiographic protocols to identify multiple myeloma bone lesions.",
author = "Faria, {Karina Morais} and Brand{\~a}o, {Thais Bianca} and Silva, {Wagner Gomes} and Juliana Pereira and Neves, {Frederico Sam Paio} and Alves, {Marcelo Corr{\^e}a} and Werner Shintaku and Lopes, {Marcio Ajudarte} and Ribeiro, {Ana Carolina Prado} and Migliorati, {Cesar Augusto} and Santos-Silva, {Alan Roger}",
year = "2018",
month = "1",
day = "20",
doi = "10.4317/medoral.22123",
language = "English (US)",
volume = "23",
pages = "e38--e47",
journal = "Medicina Oral, Patologia Oral y Cirugia Bucal",
issn = "1698-4447",
publisher = "Medicina Oral, Patologia Oral y Cirugia Bucal",
number = "1",

}

TY - JOUR

T1 - Panoramic and skull imaging may aid in the identification of multiple myeloma lesions

AU - Faria, Karina Morais

AU - Brandão, Thais Bianca

AU - Silva, Wagner Gomes

AU - Pereira, Juliana

AU - Neves, Frederico Sam Paio

AU - Alves, Marcelo Corrêa

AU - Shintaku, Werner

AU - Lopes, Marcio Ajudarte

AU - Ribeiro, Ana Carolina Prado

AU - Migliorati, Cesar Augusto

AU - Santos-Silva, Alan Roger

PY - 2018/1/20

Y1 - 2018/1/20

N2 - Background: The purpose of this study was to investigate the presence of punched-out lesions in craniofacial bones using three different radiographic protocols in a large cohort of patients. Material and Methods: One hundred fifty-five MM patients were evaluated using panoramic and skull (frontal and lateral) radiographs, which were performed in all patients at the time of MM diagnosis. The diagnostic potential for detecting punched-out lesions was compared among the radiographic techniques. Results: MM punched-out lesions were identified in 135 (87%) panoramic radiographs, 141 (91%) frontal and 144 (93%) lateral skull radiographs. Punched out-lesions were synchronously present in skull and jawbones in 129 (83.23 %) cases. The lesions were detected exclusively in skull in 18 (11.61%) cases and exclusively in jawbones in 6 (3.87%) cases. Punched out-lesion mainly affected the skull and the jawbones in a synchronous way (p<0.001) rather than separately. Conclusions: All investigated radiographic techniques (panoramic, frontal and lateral skull approaches) demonstrated high detection rates for MM punched-out lesions in craniofacial bones. Panoramic radiography may aid to the radiographic protocols to identify multiple myeloma bone lesions.

AB - Background: The purpose of this study was to investigate the presence of punched-out lesions in craniofacial bones using three different radiographic protocols in a large cohort of patients. Material and Methods: One hundred fifty-five MM patients were evaluated using panoramic and skull (frontal and lateral) radiographs, which were performed in all patients at the time of MM diagnosis. The diagnostic potential for detecting punched-out lesions was compared among the radiographic techniques. Results: MM punched-out lesions were identified in 135 (87%) panoramic radiographs, 141 (91%) frontal and 144 (93%) lateral skull radiographs. Punched out-lesions were synchronously present in skull and jawbones in 129 (83.23 %) cases. The lesions were detected exclusively in skull in 18 (11.61%) cases and exclusively in jawbones in 6 (3.87%) cases. Punched out-lesion mainly affected the skull and the jawbones in a synchronous way (p<0.001) rather than separately. Conclusions: All investigated radiographic techniques (panoramic, frontal and lateral skull approaches) demonstrated high detection rates for MM punched-out lesions in craniofacial bones. Panoramic radiography may aid to the radiographic protocols to identify multiple myeloma bone lesions.

UR - http://www.scopus.com/inward/record.url?scp=85041299537&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85041299537&partnerID=8YFLogxK

U2 - 10.4317/medoral.22123

DO - 10.4317/medoral.22123

M3 - Article

VL - 23

SP - e38-e47

JO - Medicina Oral, Patologia Oral y Cirugia Bucal

JF - Medicina Oral, Patologia Oral y Cirugia Bucal

SN - 1698-4447

IS - 1

M1 - 22123

ER -