Pediatric traumatic brain injury

Correlation of intracranial and arterial pressure signals

Michael L. Daley, Sarah Patterson, Anthony Marmarou, Charles Leffler, Gregory Stidham

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Laboratory studies have shown that correlation analysis applied to the intracranial and arterial pressure signals provides a means for detecting loss of vascular tone during massive vasodilation induced by deep hypercapnia. In this preliminary clinical study, the same correlation analysis technique was used to evaluate changes of intracranial and arterial pressure in pediatric patients with traumatic brain injury. Clinical and laboratory recordings were similar. In three of the four cases studied strong correlations (r>.8) were demonstrated between intracranial and arterial pressure. In two cases, these strong correlations occurred when intracranial pressure was below 20 mm of Hg. The results of this study suggest that extensive cerebral vasodilation can occur during mild increases of intracranial pressure and with high Glasgow scale ratings on admission.

Original languageEnglish (US)
Pages (from-to)169-170
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Issue number1
StatePublished - 1996
Externally publishedYes

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Pediatrics
Intracranial Pressure
Brain
Arterial Pressure
Vasodilation
Intracranial Hypertension
Hypercapnia
Blood Vessels
Traumatic Brain Injury

All Science Journal Classification (ASJC) codes

  • Bioengineering

Cite this

Pediatric traumatic brain injury : Correlation of intracranial and arterial pressure signals. / Daley, Michael L.; Patterson, Sarah; Marmarou, Anthony; Leffler, Charles; Stidham, Gregory.

In: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, No. 1, 1996, p. 169-170.

Research output: Contribution to journalArticle

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