Peripherally inserted central venous catheter-associated thrombosis

Retrospective analysis of clinical risk factors in adult patients

Melissa M. King, Mark Rasnake, Rechell G. Rodriguez, Nancy J. Riley, Jason A. Stamm

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

BACKGROUND: Peripherally inserted central catheters (PICC) are common venous access devices. Clinical conditions and therapies that increase the risk of PICC-associated thrombosis have not been studied. METHODS: We performed a retrospective case-control analysis of all adult patients who underwent placement of a PICC at our hospital over a three-year period (n = 1296). Clinical variables examined were indication for PICC placement, active cancer treatment, history of DVT, diabetes mellitus, and use of prophylactic anticoagulation. RESULTS: The overall incidence of PICC-associated DVT was 2% (n = 27). Active cancer therapy was significantly associated with PICC-associated DVT (OR 3.5, 95% CI 1.3-9.8). The use of prophylactic anticoagulation did not reduce this risk. CONCLUSIONS: Patients who suffered a PICC-associated DVT were more likely to be undergoing treatment for cancer. This risk was not lowered by the use of prophylactic anticoagulation. These results suggest a need for prospective studies on effective anticoagulation for patients at high risk for PICC-associated DVT.

Original languageEnglish (US)
Pages (from-to)1073-1077
Number of pages5
JournalSouthern medical journal
Volume99
Issue number10
DOIs
StatePublished - Oct 1 2006

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Upper Extremity Deep Vein Thrombosis
Catheters
Neoplasms
Central Venous Catheters
Therapeutics
Diabetes Mellitus
Thrombosis
Prospective Studies
Equipment and Supplies
Incidence

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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Peripherally inserted central venous catheter-associated thrombosis : Retrospective analysis of clinical risk factors in adult patients. / King, Melissa M.; Rasnake, Mark; Rodriguez, Rechell G.; Riley, Nancy J.; Stamm, Jason A.

In: Southern medical journal, Vol. 99, No. 10, 01.10.2006, p. 1073-1077.

Research output: Contribution to journalArticle

King, Melissa M. ; Rasnake, Mark ; Rodriguez, Rechell G. ; Riley, Nancy J. ; Stamm, Jason A. / Peripherally inserted central venous catheter-associated thrombosis : Retrospective analysis of clinical risk factors in adult patients. In: Southern medical journal. 2006 ; Vol. 99, No. 10. pp. 1073-1077.
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AU - Stamm, Jason A.

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