Peroxidase Antimicrobial System of Human Saliva

Hypothiocyanite Levels in Resting and Stimulated Saliva

J. Tenovuo, K. M. Pruitt, Edwin Thomas

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

The antimicrobial oxidizing agent hypothiocyanite ion (OSCN-) was measured in resting (drooling) and stimulated (expectorated) whole saliva. Stimulation of the saliva flow rate resulted in a rapid decrease in OSCN- concentration, whereas the thiocyanate ion (SCN—) concentration and peroxidase activity were increased. The decrease in OSCN — levels was greater than could be accounted for by dilution of the whole saliva volume. Assuming that the antimicrobial activity of the salivary peroxidase system is proportional to OSCN- concentration, this system may be more effective in resting saliva than in stimulated saliva.

Original languageEnglish (US)
Pages (from-to)982-985
Number of pages4
JournalJournal of Dental Research
Volume61
Issue number8
DOIs
StatePublished - Jan 1 1982

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Saliva
Peroxidase
Sialorrhea
Anti-Infective Agents
Oxidants
hypothiocyanite ion

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

Peroxidase Antimicrobial System of Human Saliva : Hypothiocyanite Levels in Resting and Stimulated Saliva. / Tenovuo, J.; Pruitt, K. M.; Thomas, Edwin.

In: Journal of Dental Research, Vol. 61, No. 8, 01.01.1982, p. 982-985.

Research output: Contribution to journalArticle

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