Pharmacokinetic profile of spectinomycin in rats

D. B. Madhura, R. Lee, Bernd Meibohm

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Following intravenous (IV) administration, the pharmacokinetics of spectinomycin in rats was found to be on par with its profile in other mammalian species including humans with respect to its overall excretion and half-life at effective concentrations. This study, however, indicates that a small fraction of the spectinomycin dose is retained in peripheral tissues for a prolonged period of time at low concentrations.

Original languageEnglish (US)
Pages (from-to)675-676
Number of pages2
JournalPharmazie
Volume68
Issue number8
DOIs
StatePublished - Aug 1 2013

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Spectinomycin
Pharmacokinetics
Intravenous Administration
Half-Life

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

Pharmacokinetic profile of spectinomycin in rats. / Madhura, D. B.; Lee, R.; Meibohm, Bernd.

In: Pharmazie, Vol. 68, No. 8, 01.08.2013, p. 675-676.

Research output: Contribution to journalArticle

Madhura, D. B. ; Lee, R. ; Meibohm, Bernd. / Pharmacokinetic profile of spectinomycin in rats. In: Pharmazie. 2013 ; Vol. 68, No. 8. pp. 675-676.
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