Pharmacology of Antiepileptic Drugs

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter reviews basic anticonvulsant pharmacokinetics with emphasis on clinical aspects. It also provides an overview of pharmacogenomics and its potential application to care of epilepsy patients. The basic aspects of drug absorption, distribution, metabolism and elimination are considered, as well as the pharmacokinetic parameters pertinent to anticonvulsants. The concept of therapeutic drug monitoring is introduced. Individual differences in responses to drugs are considered in the light of recent advances in pharmacogenomics.

Original languageEnglish (US)
Title of host publicationEpilepsy in Children and Adolescents
PublisherJohn Wiley and Sons
Pages143-158
Number of pages16
ISBN (Print)9780470741238
DOIs
StatePublished - Nov 1 2012

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Pharmacogenetics
Anticonvulsants
Pharmacokinetics
Pharmacology
Drug Monitoring
Individuality
Pharmaceutical Preparations
Epilepsy
Patient Care

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Wheless, J. (2012). Pharmacology of Antiepileptic Drugs. In Epilepsy in Children and Adolescents (pp. 143-158). John Wiley and Sons. https://doi.org/10.1002/9781119998600.ch9

Pharmacology of Antiepileptic Drugs. / Wheless, James.

Epilepsy in Children and Adolescents. John Wiley and Sons, 2012. p. 143-158.

Research output: Chapter in Book/Report/Conference proceedingChapter

Wheless, J 2012, Pharmacology of Antiepileptic Drugs. in Epilepsy in Children and Adolescents. John Wiley and Sons, pp. 143-158. https://doi.org/10.1002/9781119998600.ch9
Wheless J. Pharmacology of Antiepileptic Drugs. In Epilepsy in Children and Adolescents. John Wiley and Sons. 2012. p. 143-158 https://doi.org/10.1002/9781119998600.ch9
Wheless, James. / Pharmacology of Antiepileptic Drugs. Epilepsy in Children and Adolescents. John Wiley and Sons, 2012. pp. 143-158
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