Phylogenetic and geographical relationships of hantavirus strains in eastern and western Paraguay

Kyu Chu Yong, Brook Milligan, Robert D. Owen, Douglas G. Goodin, Colleen Jonsson

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Recently, we reported the discovery of several potential rodent reservoirs of hantaviruses in western (Holochilus chacarius) and eastern Paraguay (Akodon montensis, Oligoryzomys chacoensis, and O. nigripes). Comparisons of the hantavirus S- and M-segments amplified from these four rodents revealed significant differences from each another and from other South American hantaviruses. The ALP strain from the semiarid Chaco ecoregion clustered with Leguna Negra and Rio Mamore (LN/RM), whereas the BMJ-ÑEB strain from the more humid lower Chaco ecoregion formed a clade with Oran and Bermejo. The other two strains, AAI and IP37/38, were distinct from known hantaviruses. With respect to the S-segment sequence, AAI from eastern Paraguay formed a clade with ALP/LN/RM, but its M-segment clustered with Pergamino and Maciel, suggesting a possible reassortment. AAI was found in areas experiencing rapid land cover fragmentation and change within the Interior Atlantic Forest. IP37/38 did not show any strong association with any of the known hantavirus strains.

Original languageEnglish (US)
Pages (from-to)1127-1134
Number of pages8
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume75
Issue number6
StatePublished - Dec 1 2006
Externally publishedYes

Fingerprint

Paraguay
Hantavirus
Rodentia

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Infectious Diseases
  • Virology

Cite this

Phylogenetic and geographical relationships of hantavirus strains in eastern and western Paraguay. / Yong, Kyu Chu; Milligan, Brook; Owen, Robert D.; Goodin, Douglas G.; Jonsson, Colleen.

In: American Journal of Tropical Medicine and Hygiene, Vol. 75, No. 6, 01.12.2006, p. 1127-1134.

Research output: Contribution to journalArticle

Yong, Kyu Chu ; Milligan, Brook ; Owen, Robert D. ; Goodin, Douglas G. ; Jonsson, Colleen. / Phylogenetic and geographical relationships of hantavirus strains in eastern and western Paraguay. In: American Journal of Tropical Medicine and Hygiene. 2006 ; Vol. 75, No. 6. pp. 1127-1134.
@article{a49ea133b77345de9ac877b85691eda5,
title = "Phylogenetic and geographical relationships of hantavirus strains in eastern and western Paraguay",
abstract = "Recently, we reported the discovery of several potential rodent reservoirs of hantaviruses in western (Holochilus chacarius) and eastern Paraguay (Akodon montensis, Oligoryzomys chacoensis, and O. nigripes). Comparisons of the hantavirus S- and M-segments amplified from these four rodents revealed significant differences from each another and from other South American hantaviruses. The ALP strain from the semiarid Chaco ecoregion clustered with Leguna Negra and Rio Mamore (LN/RM), whereas the BMJ-{\~N}EB strain from the more humid lower Chaco ecoregion formed a clade with Oran and Bermejo. The other two strains, AAI and IP37/38, were distinct from known hantaviruses. With respect to the S-segment sequence, AAI from eastern Paraguay formed a clade with ALP/LN/RM, but its M-segment clustered with Pergamino and Maciel, suggesting a possible reassortment. AAI was found in areas experiencing rapid land cover fragmentation and change within the Interior Atlantic Forest. IP37/38 did not show any strong association with any of the known hantavirus strains.",
author = "Yong, {Kyu Chu} and Brook Milligan and Owen, {Robert D.} and Goodin, {Douglas G.} and Colleen Jonsson",
year = "2006",
month = "12",
day = "1",
language = "English (US)",
volume = "75",
pages = "1127--1134",
journal = "American Journal of Tropical Medicine and Hygiene",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "6",

}

TY - JOUR

T1 - Phylogenetic and geographical relationships of hantavirus strains in eastern and western Paraguay

AU - Yong, Kyu Chu

AU - Milligan, Brook

AU - Owen, Robert D.

AU - Goodin, Douglas G.

AU - Jonsson, Colleen

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Recently, we reported the discovery of several potential rodent reservoirs of hantaviruses in western (Holochilus chacarius) and eastern Paraguay (Akodon montensis, Oligoryzomys chacoensis, and O. nigripes). Comparisons of the hantavirus S- and M-segments amplified from these four rodents revealed significant differences from each another and from other South American hantaviruses. The ALP strain from the semiarid Chaco ecoregion clustered with Leguna Negra and Rio Mamore (LN/RM), whereas the BMJ-ÑEB strain from the more humid lower Chaco ecoregion formed a clade with Oran and Bermejo. The other two strains, AAI and IP37/38, were distinct from known hantaviruses. With respect to the S-segment sequence, AAI from eastern Paraguay formed a clade with ALP/LN/RM, but its M-segment clustered with Pergamino and Maciel, suggesting a possible reassortment. AAI was found in areas experiencing rapid land cover fragmentation and change within the Interior Atlantic Forest. IP37/38 did not show any strong association with any of the known hantavirus strains.

AB - Recently, we reported the discovery of several potential rodent reservoirs of hantaviruses in western (Holochilus chacarius) and eastern Paraguay (Akodon montensis, Oligoryzomys chacoensis, and O. nigripes). Comparisons of the hantavirus S- and M-segments amplified from these four rodents revealed significant differences from each another and from other South American hantaviruses. The ALP strain from the semiarid Chaco ecoregion clustered with Leguna Negra and Rio Mamore (LN/RM), whereas the BMJ-ÑEB strain from the more humid lower Chaco ecoregion formed a clade with Oran and Bermejo. The other two strains, AAI and IP37/38, were distinct from known hantaviruses. With respect to the S-segment sequence, AAI from eastern Paraguay formed a clade with ALP/LN/RM, but its M-segment clustered with Pergamino and Maciel, suggesting a possible reassortment. AAI was found in areas experiencing rapid land cover fragmentation and change within the Interior Atlantic Forest. IP37/38 did not show any strong association with any of the known hantavirus strains.

UR - http://www.scopus.com/inward/record.url?scp=38849093337&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38849093337&partnerID=8YFLogxK

M3 - Article

VL - 75

SP - 1127

EP - 1134

JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

SN - 0002-9637

IS - 6

ER -