Phylogenetic conservatism in the presence of a neurotensin-related hexapeptide in neurons of globus pallidus

Anton Reiner, Robert E. Carraway

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The vast majority of the pallidal neurons of the hamster, pigeon, caiman and turtle basal telencephalon were positively labeled by an antiserum against LANT-6, a neurotensin-like hexapeptide. In sharks also, LANT-6-positive neurons were observed in the apparent equivalent of the globus pallidus. These results, which imply the coexistence of a LANT-6-like peptide with gamma-aminobutyric acid (GABA) in pallidal neurons, suggest that a LANT-6-like peptide may be an important and evolutionarily conserved neurotransmitter/neuromodulator in pallidal neurons.

Original languageEnglish (US)
Pages (from-to)365-371
Number of pages7
JournalBrain Research
Volume341
Issue number2
DOIs
StatePublished - Aug 26 1985

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Globus Pallidus
Politics
Neurons
Neurotransmitter Agents
Alligators and Crocodiles
Sharks
Telencephalon
Neurotensin
Peptides
Turtles
Columbidae
Cricetinae
gamma-Aminobutyric Acid
Immune Sera
neurotensin-related hexapeptide

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Developmental Biology
  • Clinical Neurology

Cite this

Phylogenetic conservatism in the presence of a neurotensin-related hexapeptide in neurons of globus pallidus. / Reiner, Anton; Carraway, Robert E.

In: Brain Research, Vol. 341, No. 2, 26.08.1985, p. 365-371.

Research output: Contribution to journalArticle

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