Physiology of the Endocannabinoid System During Development

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The endocannabinoid (eCB) system comprises endogenously produced cannabinoids (CBs), enzymes of their production and degradation, and CB-sensing receptors and transporters. The eCB system plays a critical role in virtually all stages of animal development. Studies on eCB system components and their physiological role have gained increasing attention with the rising legalization and medical use of marijuana products. The latter represent exogenous interventions that target the eCB system. This chapter summarizes knowledge in the field of CB contribution to gametogenesis, fertilization, embryo implantation, fetal development, birth, and adolescence-equivalent periods of ontogenesis. The material is complemented by the overview of data from our laboratory documenting the functional presence of the eCB system within cerebral arteries of baboons at different stages of development.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages13-37
Number of pages25
DOIs
StatePublished - Jan 1 2019

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1162
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Fingerprint

Endocannabinoids
Cerebral Arteries
Cannabinoids
Papio
Physiology
Cannabis
Medical Marijuana
Embryonic and Fetal Development
Gametogenesis
Cannabinoid Receptors
Switzerland
Fertilization
Animals
Parturition
Degradation
Enzymes

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Bukiya, A. (2019). Physiology of the Endocannabinoid System During Development. In Advances in Experimental Medicine and Biology (pp. 13-37). (Advances in Experimental Medicine and Biology; Vol. 1162). Springer New York LLC. https://doi.org/10.1007/978-3-030-21737-2_2

Physiology of the Endocannabinoid System During Development. / Bukiya, Anna.

Advances in Experimental Medicine and Biology. Springer New York LLC, 2019. p. 13-37 (Advances in Experimental Medicine and Biology; Vol. 1162).

Research output: Chapter in Book/Report/Conference proceedingChapter

Bukiya, A 2019, Physiology of the Endocannabinoid System During Development. in Advances in Experimental Medicine and Biology. Advances in Experimental Medicine and Biology, vol. 1162, Springer New York LLC, pp. 13-37. https://doi.org/10.1007/978-3-030-21737-2_2
Bukiya A. Physiology of the Endocannabinoid System During Development. In Advances in Experimental Medicine and Biology. Springer New York LLC. 2019. p. 13-37. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-3-030-21737-2_2
Bukiya, Anna. / Physiology of the Endocannabinoid System During Development. Advances in Experimental Medicine and Biology. Springer New York LLC, 2019. pp. 13-37 (Advances in Experimental Medicine and Biology).
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