Pneumonia and ARDS in patients receiving mechanical ventilation: Diagnostic accuracy of chest radiography

Helen T. Winer-Muram, Sanford A. Rubin, James V. Ellis, S. Gregory Jennings, Kristopher L. Arheart, Richard G. Wunderink, Kenneth V. Leeper, Gianfranco Meduri

Research output: Contribution to journalArticle

111 Citations (Scopus)

Abstract

This study was done to evaluate the diagnostic accuracy of bedside chest radiography for pneumonia, adult respiratory distress syndrome (ARDS), or both in patients receiving mechanical ventilation. The series consisted of 40 patients; diagnostic accuracy was defined as the area under the receiver operating characteristic curve. Overall diagnostic accuracy for ARDS was 0.84. Overall diagnostic accuracy for pneumonia was 0.52. Review of previous radiographs and knowledge of clinical data did not enhance diagnostic accuracy for ARDS or pneumonia. Diagnostic accuracy for pneumonia was minimally reduced when ARDS was present. There was an increase in false-negative results because the diffuse areas of increased opacity in ARDS obscured the radiographic features of pneumonia. The authors conclude that chest radiography is of limited value for the diagnosis of pneumonia in patients receiving mechanical ventilation. The high false-negative and false-positive ratings for pneumonia resulted in a low diagnostic accuracy. The high diagnostic accuracy for ARDS was primarily due to the well-defined radiographic appearance of ARDS and few false-positive ratings.

Original languageEnglish (US)
Pages (from-to)479-485
Number of pages7
JournalRadiology
Volume188
Issue number2
DOIs
StatePublished - Jan 1 1993

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Adult Respiratory Distress Syndrome
Artificial Respiration
Radiography
Pneumonia
Thorax
ROC Curve

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Winer-Muram, H. T., Rubin, S. A., Ellis, J. V., Jennings, S. G., Arheart, K. L., Wunderink, R. G., ... Meduri, G. (1993). Pneumonia and ARDS in patients receiving mechanical ventilation: Diagnostic accuracy of chest radiography. Radiology, 188(2), 479-485. https://doi.org/10.1148/radiology.188.2.8327701

Pneumonia and ARDS in patients receiving mechanical ventilation : Diagnostic accuracy of chest radiography. / Winer-Muram, Helen T.; Rubin, Sanford A.; Ellis, James V.; Jennings, S. Gregory; Arheart, Kristopher L.; Wunderink, Richard G.; Leeper, Kenneth V.; Meduri, Gianfranco.

In: Radiology, Vol. 188, No. 2, 01.01.1993, p. 479-485.

Research output: Contribution to journalArticle

Winer-Muram, HT, Rubin, SA, Ellis, JV, Jennings, SG, Arheart, KL, Wunderink, RG, Leeper, KV & Meduri, G 1993, 'Pneumonia and ARDS in patients receiving mechanical ventilation: Diagnostic accuracy of chest radiography', Radiology, vol. 188, no. 2, pp. 479-485. https://doi.org/10.1148/radiology.188.2.8327701
Winer-Muram HT, Rubin SA, Ellis JV, Jennings SG, Arheart KL, Wunderink RG et al. Pneumonia and ARDS in patients receiving mechanical ventilation: Diagnostic accuracy of chest radiography. Radiology. 1993 Jan 1;188(2):479-485. https://doi.org/10.1148/radiology.188.2.8327701
Winer-Muram, Helen T. ; Rubin, Sanford A. ; Ellis, James V. ; Jennings, S. Gregory ; Arheart, Kristopher L. ; Wunderink, Richard G. ; Leeper, Kenneth V. ; Meduri, Gianfranco. / Pneumonia and ARDS in patients receiving mechanical ventilation : Diagnostic accuracy of chest radiography. In: Radiology. 1993 ; Vol. 188, No. 2. pp. 479-485.
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