Polymerase chain reaction and its uses as a diagnostic tool for cardiovascular disease

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The polymerase chain reaction (PCR), initially developed approximately a decade ago by Kary Mullis, has revolutionized the basic science and clinical research study of human disease. The beauty and utility of this method derive from its simplicity and automation. PCR amplifies a single copy of DNA sequence into millions of identical copies in a matter of hours, allowing rapid detection of subtle differences in sequence, gene cloning, and mutation analysis, among other uses. In this review, the basic technique of PCR and its applications as a diagnostic tool for cardiovascular disease are discussed.

Original languageEnglish (US)
Pages (from-to)175-185
Number of pages11
JournalTrends in Cardiovascular Medicine
Volume5
Issue number5
DOIs
StatePublished - Jan 1 1995
Externally publishedYes

Fingerprint

Cardiovascular Diseases
Polymerase Chain Reaction
Beauty
Automation
Organism Cloning
Mutation
Research
Genes
Clinical Studies

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Polymerase chain reaction and its uses as a diagnostic tool for cardiovascular disease. / Towbin, Jeffrey.

In: Trends in Cardiovascular Medicine, Vol. 5, No. 5, 01.01.1995, p. 175-185.

Research output: Contribution to journalArticle

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