Post-traumatic Cutaneous Mucormycosis in Diabetes Mellitus: Short-term Antifungal Therapy

Kathleen Ryan-Poirier, Robert M. Eiseman, James Beaty, Philip G. Hunt, George A. Burghen, Robert J. Leggiadro

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Mucormycosis is infrequently encountered in the pediatric population in any of its forms (nasopharyngeal, disseminated, pulmonary, or cutaneous) and generally is associated with the immunocompromised host. We present an adolescent with poorly controlled diabetes mellitus who developed a progressive skin lesion 3 weeks after a motor vehicle accident. Rhizopus species was isolated from the lesion, and the biopsy revealed a fungal vasculopathy. Control of her diabetes, aggressive surgical intervention and a 10-day course of antifungal therapy (amphotericin B) resulted in a favorable outcome. This article illustrates the importance of considering cutaneous fungal infections, especially those in the class zygomycetes, in the diabetic patient with unusual, severe or persistent skin lesions. Early recognition is essential in order to avoid morbidity and mortality from this unusual opportunistic infection.

Original languageEnglish (US)
Pages (from-to)609-612
Number of pages4
JournalClinical Pediatrics
Volume27
Issue number12
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

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Mucormycosis
Diabetes Mellitus
Skin
Rhizopus
Mycoses
Opportunistic Infections
Immunocompromised Host
Amphotericin B
Motor Vehicles
Therapeutics
Accidents
Pediatrics
Morbidity
Biopsy
Lung
Mortality
Population

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

Ryan-Poirier, K., Eiseman, R. M., Beaty, J., Hunt, P. G., Burghen, G. A., & Leggiadro, R. J. (1988). Post-traumatic Cutaneous Mucormycosis in Diabetes Mellitus: Short-term Antifungal Therapy. Clinical Pediatrics, 27(12), 609-612. https://doi.org/10.1177/000992288802701209

Post-traumatic Cutaneous Mucormycosis in Diabetes Mellitus : Short-term Antifungal Therapy. / Ryan-Poirier, Kathleen; Eiseman, Robert M.; Beaty, James; Hunt, Philip G.; Burghen, George A.; Leggiadro, Robert J.

In: Clinical Pediatrics, Vol. 27, No. 12, 01.01.1988, p. 609-612.

Research output: Contribution to journalArticle

Ryan-Poirier, K, Eiseman, RM, Beaty, J, Hunt, PG, Burghen, GA & Leggiadro, RJ 1988, 'Post-traumatic Cutaneous Mucormycosis in Diabetes Mellitus: Short-term Antifungal Therapy', Clinical Pediatrics, vol. 27, no. 12, pp. 609-612. https://doi.org/10.1177/000992288802701209
Ryan-Poirier, Kathleen ; Eiseman, Robert M. ; Beaty, James ; Hunt, Philip G. ; Burghen, George A. ; Leggiadro, Robert J. / Post-traumatic Cutaneous Mucormycosis in Diabetes Mellitus : Short-term Antifungal Therapy. In: Clinical Pediatrics. 1988 ; Vol. 27, No. 12. pp. 609-612.
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