Potential novel biomarkers of cardiovascular dysfunction & disease

Cardiotrophin-1, adipokines & galectin-3

Simona Hogas, Stefana C. Bilha, Dumitru Branisteanu, Mihai Hogas, Abduzhappar Gaipov, Mehmet Kanbay, Adrian Covic

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Cardiovascular disease is one of the main burdens of healthcare systems worldwide. Nevertheless, assessing cardiovascular risk in both apparently healthy individuals and low/high-risk patients remains a difficult issue. Already established biomarkers (e.g. brain natriuretic peptide, troponin) have significantly improved the assessment of major cardiovascular events and diseases but cannot be applied to all patients and in some cases do not provide sufficiently accurate information. In this context, new potential biomarkers that reflect various underlying pathophysiological cardiac and vascular modifications are needed. Also, a multiple biomarker evaluation that shows changes in the cardiovascular state is of interest. This review describes the role of selected markers of vascular inflammation, atherosclerosis, atherothrombosis, endothelial dysfunction and cardiovascular fibrosis in the pathogenesis and prognosis of cardiovascular disease: The potential use of cardiotrophin-1, leptin, adiponectin, resistin and galectin-3 as biomarkers for various cardiovascular conditions is discussed.

Original languageEnglish (US)
Pages (from-to)897-913
Number of pages17
JournalArchives of Medical Science
Volume13
Issue number4
DOIs
StatePublished - Jan 1 2017

Fingerprint

Galectin 3
Adipokines
Biomarkers
Cardiovascular Diseases
Blood Vessels
Resistin
Troponin
Brain Natriuretic Peptide
Adiponectin
Jurisprudence
Leptin
Atherosclerosis
Fibrosis
Inflammation
Delivery of Health Care
cardiotrophin 1

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Potential novel biomarkers of cardiovascular dysfunction & disease : Cardiotrophin-1, adipokines & galectin-3. / Hogas, Simona; Bilha, Stefana C.; Branisteanu, Dumitru; Hogas, Mihai; Gaipov, Abduzhappar; Kanbay, Mehmet; Covic, Adrian.

In: Archives of Medical Science, Vol. 13, No. 4, 01.01.2017, p. 897-913.

Research output: Contribution to journalArticle

Hogas, Simona ; Bilha, Stefana C. ; Branisteanu, Dumitru ; Hogas, Mihai ; Gaipov, Abduzhappar ; Kanbay, Mehmet ; Covic, Adrian. / Potential novel biomarkers of cardiovascular dysfunction & disease : Cardiotrophin-1, adipokines & galectin-3. In: Archives of Medical Science. 2017 ; Vol. 13, No. 4. pp. 897-913.
@article{e46b8cdfd39a409e8ef17c88b1978b09,
title = "Potential novel biomarkers of cardiovascular dysfunction & disease: Cardiotrophin-1, adipokines & galectin-3",
abstract = "Cardiovascular disease is one of the main burdens of healthcare systems worldwide. Nevertheless, assessing cardiovascular risk in both apparently healthy individuals and low/high-risk patients remains a difficult issue. Already established biomarkers (e.g. brain natriuretic peptide, troponin) have significantly improved the assessment of major cardiovascular events and diseases but cannot be applied to all patients and in some cases do not provide sufficiently accurate information. In this context, new potential biomarkers that reflect various underlying pathophysiological cardiac and vascular modifications are needed. Also, a multiple biomarker evaluation that shows changes in the cardiovascular state is of interest. This review describes the role of selected markers of vascular inflammation, atherosclerosis, atherothrombosis, endothelial dysfunction and cardiovascular fibrosis in the pathogenesis and prognosis of cardiovascular disease: The potential use of cardiotrophin-1, leptin, adiponectin, resistin and galectin-3 as biomarkers for various cardiovascular conditions is discussed.",
author = "Simona Hogas and Bilha, {Stefana C.} and Dumitru Branisteanu and Mihai Hogas and Abduzhappar Gaipov and Mehmet Kanbay and Adrian Covic",
year = "2017",
month = "1",
day = "1",
doi = "10.5114/aoms.2016.58664",
language = "English (US)",
volume = "13",
pages = "897--913",
journal = "Archives of Medical Science",
issn = "1734-1922",
publisher = "Termedia Publishing House Ltd.",
number = "4",

}

TY - JOUR

T1 - Potential novel biomarkers of cardiovascular dysfunction & disease

T2 - Cardiotrophin-1, adipokines & galectin-3

AU - Hogas, Simona

AU - Bilha, Stefana C.

AU - Branisteanu, Dumitru

AU - Hogas, Mihai

AU - Gaipov, Abduzhappar

AU - Kanbay, Mehmet

AU - Covic, Adrian

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Cardiovascular disease is one of the main burdens of healthcare systems worldwide. Nevertheless, assessing cardiovascular risk in both apparently healthy individuals and low/high-risk patients remains a difficult issue. Already established biomarkers (e.g. brain natriuretic peptide, troponin) have significantly improved the assessment of major cardiovascular events and diseases but cannot be applied to all patients and in some cases do not provide sufficiently accurate information. In this context, new potential biomarkers that reflect various underlying pathophysiological cardiac and vascular modifications are needed. Also, a multiple biomarker evaluation that shows changes in the cardiovascular state is of interest. This review describes the role of selected markers of vascular inflammation, atherosclerosis, atherothrombosis, endothelial dysfunction and cardiovascular fibrosis in the pathogenesis and prognosis of cardiovascular disease: The potential use of cardiotrophin-1, leptin, adiponectin, resistin and galectin-3 as biomarkers for various cardiovascular conditions is discussed.

AB - Cardiovascular disease is one of the main burdens of healthcare systems worldwide. Nevertheless, assessing cardiovascular risk in both apparently healthy individuals and low/high-risk patients remains a difficult issue. Already established biomarkers (e.g. brain natriuretic peptide, troponin) have significantly improved the assessment of major cardiovascular events and diseases but cannot be applied to all patients and in some cases do not provide sufficiently accurate information. In this context, new potential biomarkers that reflect various underlying pathophysiological cardiac and vascular modifications are needed. Also, a multiple biomarker evaluation that shows changes in the cardiovascular state is of interest. This review describes the role of selected markers of vascular inflammation, atherosclerosis, atherothrombosis, endothelial dysfunction and cardiovascular fibrosis in the pathogenesis and prognosis of cardiovascular disease: The potential use of cardiotrophin-1, leptin, adiponectin, resistin and galectin-3 as biomarkers for various cardiovascular conditions is discussed.

UR - http://www.scopus.com/inward/record.url?scp=85020930989&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85020930989&partnerID=8YFLogxK

U2 - 10.5114/aoms.2016.58664

DO - 10.5114/aoms.2016.58664

M3 - Article

VL - 13

SP - 897

EP - 913

JO - Archives of Medical Science

JF - Archives of Medical Science

SN - 1734-1922

IS - 4

ER -