Predicting neonatal morbidity after perinatal asphyxia

A scoring system

Ronald J. Portman, Brian S. Carter, Mark Gaylord, M. Gail Murphy, Rita E. Thieme, Gerald B. Merenstein

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Predicting immediate neonatal morbidity after perinatal asphyxia has been difficult. A review of asphyxiated neonates ≥36 weeks' gestation admitted to The Chidlren's Hospital Newborn Intensive Care Unit in 1983 was conducted to devise a scoring system that would rapidly predict organ dysfunction observed in the immediate neonatal period. Comparison of potential score components to morbidity by multiple regression analysis yielded significant association with abnormalities in fetal heart rate monitoring, the 5-minute Apgar score, and neonatal base deficit. A scoring system was devised whose sensitivity (93.8%) and specificity (81.3%) were more predictive than any of its individual components. Prospective analysis in a similar population in 1984 validated its ability to distinguish severe from moderate morbidity after asphyxia. Positive predictive value for the score in the combined study groups (n = 98) was 79% and the negative predictive value was 83%. The scoring system may offer a rapid and accurate prediction of organ dysfunction in the immediate neonatal period after asphyxia.

Original languageEnglish (US)
Pages (from-to)174-182
Number of pages9
JournalAmerican Journal of Obstetrics and Gynecology
Volume162
Issue number1
DOIs
StatePublished - Jan 1 1990

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Asphyxia
Morbidity
Fetal Heart Rate
Apgar Score
Neonatal Intensive Care Units
Regression Analysis
Sensitivity and Specificity
Pregnancy
Population

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

Cite this

Predicting neonatal morbidity after perinatal asphyxia : A scoring system. / Portman, Ronald J.; Carter, Brian S.; Gaylord, Mark; Murphy, M. Gail; Thieme, Rita E.; Merenstein, Gerald B.

In: American Journal of Obstetrics and Gynecology, Vol. 162, No. 1, 01.01.1990, p. 174-182.

Research output: Contribution to journalArticle

Portman, Ronald J. ; Carter, Brian S. ; Gaylord, Mark ; Murphy, M. Gail ; Thieme, Rita E. ; Merenstein, Gerald B. / Predicting neonatal morbidity after perinatal asphyxia : A scoring system. In: American Journal of Obstetrics and Gynecology. 1990 ; Vol. 162, No. 1. pp. 174-182.
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