Predicting outcome after listing for heart transplantation in children

Comparison of kaplan-meier and parametric competing risk analysis

D. C. McGiffin, D. C. Naftel, J. K. Kirklin, W. R. Morrow, Jeffrey Towbin, R. Shaddy, J. Alejos, A. Rossi, E. Frazier, K. Ainley, K. J. Heilman, D. K. Pacheao, R. Sterba, L. Latson, C. Fraser, R. Fitzgerald, L. Platt, R. S. Appleton, M. Kurbat, B. Friedman & 57 others F. J. Fricker, T. Fleeger, E. Pahl, P. Stapleton, W. S. Ring, M. Copeland, B. Clark, B. Sands, L. J. Addonizio, J. Douglas, D. Knauf, K. Harker, L. J. West, J. Gildner, R. L. Caldwell, T. Flaspohler, R. E. Chinnock, J. Johnston, S. Robie, M. Mullen, M. A. Laff, C. G.A. McGregor, P. Henke, S. Suddendorf, M. Timmons, W. Moskowitz, M. Flattery, A. Cabalka, M. O'Kane, F. Hoffman, N. Seimers, P. Bruhn, T. Reutzez, M. Courtney, M. D. Reller, R. Starling, C. Holt, E. Bullock, K. G. Zahka, D. Hanisch, C. Canter, S. Bash, C. E. Stubles, S. Faulkner, M. L. Stanstrom, D. Bernstein, P. Gamberg, J. Price, M. M. Boucek, C. Mashburn, M. Luna, D. Crowley, L. Callow, R. Boucek, S. Disano, D. A. Dodd, J. Burger

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

After listing for pediatric heart transplantation, at any point in time one of the following possibilities could have occurred; death, transplantation, removal from the list because of clinical improvement, or continuing to wait. In the setting of those competing outcomes, the Kaplan- Meier estimate portrays the time-relatedness of an event while ignoring the effect of the other possible outcomes. The competing outcomes method, however, depicts the time relatedness of an event while solving for all possible events simultaneously. The competing outcomes method may potentially provide more accurate information regarding the actual proportion of patients experiencing an outcome after listing.

Original languageEnglish (US)
Pages (from-to)713-722
Number of pages10
JournalJournal of Heart and Lung Transplantation
Volume16
Issue number7
StatePublished - Jan 1 1997

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Heart Transplantation
Kaplan-Meier Estimate
Transplantation
Pediatrics

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

Cite this

Predicting outcome after listing for heart transplantation in children : Comparison of kaplan-meier and parametric competing risk analysis. / McGiffin, D. C.; Naftel, D. C.; Kirklin, J. K.; Morrow, W. R.; Towbin, Jeffrey; Shaddy, R.; Alejos, J.; Rossi, A.; Frazier, E.; Ainley, K.; Heilman, K. J.; Pacheao, D. K.; Sterba, R.; Latson, L.; Fraser, C.; Fitzgerald, R.; Platt, L.; Appleton, R. S.; Kurbat, M.; Friedman, B.; Fricker, F. J.; Fleeger, T.; Pahl, E.; Stapleton, P.; Ring, W. S.; Copeland, M.; Clark, B.; Sands, B.; Addonizio, L. J.; Douglas, J.; Knauf, D.; Harker, K.; West, L. J.; Gildner, J.; Caldwell, R. L.; Flaspohler, T.; Chinnock, R. E.; Johnston, J.; Robie, S.; Mullen, M.; Laff, M. A.; McGregor, C. G.A.; Henke, P.; Suddendorf, S.; Timmons, M.; Moskowitz, W.; Flattery, M.; Cabalka, A.; O'Kane, M.; Hoffman, F.; Seimers, N.; Bruhn, P.; Reutzez, T.; Courtney, M.; Reller, M. D.; Starling, R.; Holt, C.; Bullock, E.; Zahka, K. G.; Hanisch, D.; Canter, C.; Bash, S.; Stubles, C. E.; Faulkner, S.; Stanstrom, M. L.; Bernstein, D.; Gamberg, P.; Price, J.; Boucek, M. M.; Mashburn, C.; Luna, M.; Crowley, D.; Callow, L.; Boucek, R.; Disano, S.; Dodd, D. A.; Burger, J.

In: Journal of Heart and Lung Transplantation, Vol. 16, No. 7, 01.01.1997, p. 713-722.

Research output: Contribution to journalArticle

McGiffin, DC, Naftel, DC, Kirklin, JK, Morrow, WR, Towbin, J, Shaddy, R, Alejos, J, Rossi, A, Frazier, E, Ainley, K, Heilman, KJ, Pacheao, DK, Sterba, R, Latson, L, Fraser, C, Fitzgerald, R, Platt, L, Appleton, RS, Kurbat, M, Friedman, B, Fricker, FJ, Fleeger, T, Pahl, E, Stapleton, P, Ring, WS, Copeland, M, Clark, B, Sands, B, Addonizio, LJ, Douglas, J, Knauf, D, Harker, K, West, LJ, Gildner, J, Caldwell, RL, Flaspohler, T, Chinnock, RE, Johnston, J, Robie, S, Mullen, M, Laff, MA, McGregor, CGA, Henke, P, Suddendorf, S, Timmons, M, Moskowitz, W, Flattery, M, Cabalka, A, O'Kane, M, Hoffman, F, Seimers, N, Bruhn, P, Reutzez, T, Courtney, M, Reller, MD, Starling, R, Holt, C, Bullock, E, Zahka, KG, Hanisch, D, Canter, C, Bash, S, Stubles, CE, Faulkner, S, Stanstrom, ML, Bernstein, D, Gamberg, P, Price, J, Boucek, MM, Mashburn, C, Luna, M, Crowley, D, Callow, L, Boucek, R, Disano, S, Dodd, DA & Burger, J 1997, 'Predicting outcome after listing for heart transplantation in children: Comparison of kaplan-meier and parametric competing risk analysis', Journal of Heart and Lung Transplantation, vol. 16, no. 7, pp. 713-722.
McGiffin, D. C. ; Naftel, D. C. ; Kirklin, J. K. ; Morrow, W. R. ; Towbin, Jeffrey ; Shaddy, R. ; Alejos, J. ; Rossi, A. ; Frazier, E. ; Ainley, K. ; Heilman, K. J. ; Pacheao, D. K. ; Sterba, R. ; Latson, L. ; Fraser, C. ; Fitzgerald, R. ; Platt, L. ; Appleton, R. S. ; Kurbat, M. ; Friedman, B. ; Fricker, F. J. ; Fleeger, T. ; Pahl, E. ; Stapleton, P. ; Ring, W. S. ; Copeland, M. ; Clark, B. ; Sands, B. ; Addonizio, L. J. ; Douglas, J. ; Knauf, D. ; Harker, K. ; West, L. J. ; Gildner, J. ; Caldwell, R. L. ; Flaspohler, T. ; Chinnock, R. E. ; Johnston, J. ; Robie, S. ; Mullen, M. ; Laff, M. A. ; McGregor, C. G.A. ; Henke, P. ; Suddendorf, S. ; Timmons, M. ; Moskowitz, W. ; Flattery, M. ; Cabalka, A. ; O'Kane, M. ; Hoffman, F. ; Seimers, N. ; Bruhn, P. ; Reutzez, T. ; Courtney, M. ; Reller, M. D. ; Starling, R. ; Holt, C. ; Bullock, E. ; Zahka, K. G. ; Hanisch, D. ; Canter, C. ; Bash, S. ; Stubles, C. E. ; Faulkner, S. ; Stanstrom, M. L. ; Bernstein, D. ; Gamberg, P. ; Price, J. ; Boucek, M. M. ; Mashburn, C. ; Luna, M. ; Crowley, D. ; Callow, L. ; Boucek, R. ; Disano, S. ; Dodd, D. A. ; Burger, J. / Predicting outcome after listing for heart transplantation in children : Comparison of kaplan-meier and parametric competing risk analysis. In: Journal of Heart and Lung Transplantation. 1997 ; Vol. 16, No. 7. pp. 713-722.
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abstract = "After listing for pediatric heart transplantation, at any point in time one of the following possibilities could have occurred; death, transplantation, removal from the list because of clinical improvement, or continuing to wait. In the setting of those competing outcomes, the Kaplan- Meier estimate portrays the time-relatedness of an event while ignoring the effect of the other possible outcomes. The competing outcomes method, however, depicts the time relatedness of an event while solving for all possible events simultaneously. The competing outcomes method may potentially provide more accurate information regarding the actual proportion of patients experiencing an outcome after listing.",
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T2 - Comparison of kaplan-meier and parametric competing risk analysis

AU - McGiffin, D. C.

AU - Naftel, D. C.

AU - Kirklin, J. K.

AU - Morrow, W. R.

AU - Towbin, Jeffrey

AU - Shaddy, R.

AU - Alejos, J.

AU - Rossi, A.

AU - Frazier, E.

AU - Ainley, K.

AU - Heilman, K. J.

AU - Pacheao, D. K.

AU - Sterba, R.

AU - Latson, L.

AU - Fraser, C.

AU - Fitzgerald, R.

AU - Platt, L.

AU - Appleton, R. S.

AU - Kurbat, M.

AU - Friedman, B.

AU - Fricker, F. J.

AU - Fleeger, T.

AU - Pahl, E.

AU - Stapleton, P.

AU - Ring, W. S.

AU - Copeland, M.

AU - Clark, B.

AU - Sands, B.

AU - Addonizio, L. J.

AU - Douglas, J.

AU - Knauf, D.

AU - Harker, K.

AU - West, L. J.

AU - Gildner, J.

AU - Caldwell, R. L.

AU - Flaspohler, T.

AU - Chinnock, R. E.

AU - Johnston, J.

AU - Robie, S.

AU - Mullen, M.

AU - Laff, M. A.

AU - McGregor, C. G.A.

AU - Henke, P.

AU - Suddendorf, S.

AU - Timmons, M.

AU - Moskowitz, W.

AU - Flattery, M.

AU - Cabalka, A.

AU - O'Kane, M.

AU - Hoffman, F.

AU - Seimers, N.

AU - Bruhn, P.

AU - Reutzez, T.

AU - Courtney, M.

AU - Reller, M. D.

AU - Starling, R.

AU - Holt, C.

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AU - Stanstrom, M. L.

AU - Bernstein, D.

AU - Gamberg, P.

AU - Price, J.

AU - Boucek, M. M.

AU - Mashburn, C.

AU - Luna, M.

AU - Crowley, D.

AU - Callow, L.

AU - Boucek, R.

AU - Disano, S.

AU - Dodd, D. A.

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