Predictive value of current imaging modalities for the detection of urolithiasis during pregnancy

A multicenter, longitudinal study

Wesley White, Elizabeth B. Johnson, Nikki Zite, John Beddies, Amy E. Krambeck, Elias Hyams, Tracy Marien, Ojas Shah, Brian Matlaga, Vernon M. Pais

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Purpose: We determined the optimal imaging study by which to diagnose and treat pregnant patients with suspected urolithiasis. Materials and Methods: A retrospective, multicenter study was performed to determine the comparative accuracy of imaging modalities used before the surgical management of suspected urolithiasis in pregnant patients. Patients with a clinical suspicion of urolithiasis were evaluated with directed imaging including renal ultrasound alone, renal ultrasound and low dose computerized tomography, or renal ultrasound and magnetic resonance urography. When indicated, patients underwent therapeutic ureteroscopy. The rate of negative ureteroscopy was determined and the positive predictive values of the imaging modalities were calculated. Results: A total of 51 pregnant patients underwent ureteroscopy. The mean age of the cohort was 27 years. Mean gestational age was 24.4 weeks. Of the women 24 (47%) underwent renal ultrasound and low dose computerized tomography, 22 (43%) underwent ultrasound alone, and 5 (10%) underwent renal ultrasound and magnetic resonance urography. Negative ureteroscopy occurred in 7 of the 51 patients (14%). The rate of negative ureteroscopy among patients who underwent renal ultrasound alone, renal ultrasound and low dose computerized tomography, and renal ultrasound and magnetic resonance urography was 23%, 4.2% and 20%, respectively. The positive predictive value of computerized tomography, magnetic resonance and ultrasound was 95.8%, 80% and 77%, respectively. Conclusions: The rate of negative ureteroscopy was 14% among pregnant women undergoing intervention in our series. Of the group treated surgically after imaging with ultrasound alone, 23% had no ureteral stone, resulting in the lowest positive predictive value of the modalities used. Alternative imaging techniques, particularly low dose computerized tomography, offer improved diagnostic information that can optimize management and obviate unnecessary intervention.

Original languageEnglish (US)
Pages (from-to)931-934
Number of pages4
JournalJournal of Urology
Volume189
Issue number3
DOIs
StatePublished - Mar 1 2013
Externally publishedYes

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Urolithiasis
Ureteroscopy
Multicenter Studies
Longitudinal Studies
Kidney
Pregnancy
Tomography
Urography
Magnetic Resonance Spectroscopy
Gestational Age
Pregnant Women
Ultrasonography
Retrospective Studies

All Science Journal Classification (ASJC) codes

  • Urology

Cite this

Predictive value of current imaging modalities for the detection of urolithiasis during pregnancy : A multicenter, longitudinal study. / White, Wesley; Johnson, Elizabeth B.; Zite, Nikki; Beddies, John; Krambeck, Amy E.; Hyams, Elias; Marien, Tracy; Shah, Ojas; Matlaga, Brian; Pais, Vernon M.

In: Journal of Urology, Vol. 189, No. 3, 01.03.2013, p. 931-934.

Research output: Contribution to journalArticle

White, Wesley ; Johnson, Elizabeth B. ; Zite, Nikki ; Beddies, John ; Krambeck, Amy E. ; Hyams, Elias ; Marien, Tracy ; Shah, Ojas ; Matlaga, Brian ; Pais, Vernon M. / Predictive value of current imaging modalities for the detection of urolithiasis during pregnancy : A multicenter, longitudinal study. In: Journal of Urology. 2013 ; Vol. 189, No. 3. pp. 931-934.
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abstract = "Purpose: We determined the optimal imaging study by which to diagnose and treat pregnant patients with suspected urolithiasis. Materials and Methods: A retrospective, multicenter study was performed to determine the comparative accuracy of imaging modalities used before the surgical management of suspected urolithiasis in pregnant patients. Patients with a clinical suspicion of urolithiasis were evaluated with directed imaging including renal ultrasound alone, renal ultrasound and low dose computerized tomography, or renal ultrasound and magnetic resonance urography. When indicated, patients underwent therapeutic ureteroscopy. The rate of negative ureteroscopy was determined and the positive predictive values of the imaging modalities were calculated. Results: A total of 51 pregnant patients underwent ureteroscopy. The mean age of the cohort was 27 years. Mean gestational age was 24.4 weeks. Of the women 24 (47{\%}) underwent renal ultrasound and low dose computerized tomography, 22 (43{\%}) underwent ultrasound alone, and 5 (10{\%}) underwent renal ultrasound and magnetic resonance urography. Negative ureteroscopy occurred in 7 of the 51 patients (14{\%}). The rate of negative ureteroscopy among patients who underwent renal ultrasound alone, renal ultrasound and low dose computerized tomography, and renal ultrasound and magnetic resonance urography was 23{\%}, 4.2{\%} and 20{\%}, respectively. The positive predictive value of computerized tomography, magnetic resonance and ultrasound was 95.8{\%}, 80{\%} and 77{\%}, respectively. Conclusions: The rate of negative ureteroscopy was 14{\%} among pregnant women undergoing intervention in our series. Of the group treated surgically after imaging with ultrasound alone, 23{\%} had no ureteral stone, resulting in the lowest positive predictive value of the modalities used. Alternative imaging techniques, particularly low dose computerized tomography, offer improved diagnostic information that can optimize management and obviate unnecessary intervention.",
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AU - Beddies, John

AU - Krambeck, Amy E.

AU - Hyams, Elias

AU - Marien, Tracy

AU - Shah, Ojas

AU - Matlaga, Brian

AU - Pais, Vernon M.

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N2 - Purpose: We determined the optimal imaging study by which to diagnose and treat pregnant patients with suspected urolithiasis. Materials and Methods: A retrospective, multicenter study was performed to determine the comparative accuracy of imaging modalities used before the surgical management of suspected urolithiasis in pregnant patients. Patients with a clinical suspicion of urolithiasis were evaluated with directed imaging including renal ultrasound alone, renal ultrasound and low dose computerized tomography, or renal ultrasound and magnetic resonance urography. When indicated, patients underwent therapeutic ureteroscopy. The rate of negative ureteroscopy was determined and the positive predictive values of the imaging modalities were calculated. Results: A total of 51 pregnant patients underwent ureteroscopy. The mean age of the cohort was 27 years. Mean gestational age was 24.4 weeks. Of the women 24 (47%) underwent renal ultrasound and low dose computerized tomography, 22 (43%) underwent ultrasound alone, and 5 (10%) underwent renal ultrasound and magnetic resonance urography. Negative ureteroscopy occurred in 7 of the 51 patients (14%). The rate of negative ureteroscopy among patients who underwent renal ultrasound alone, renal ultrasound and low dose computerized tomography, and renal ultrasound and magnetic resonance urography was 23%, 4.2% and 20%, respectively. The positive predictive value of computerized tomography, magnetic resonance and ultrasound was 95.8%, 80% and 77%, respectively. Conclusions: The rate of negative ureteroscopy was 14% among pregnant women undergoing intervention in our series. Of the group treated surgically after imaging with ultrasound alone, 23% had no ureteral stone, resulting in the lowest positive predictive value of the modalities used. Alternative imaging techniques, particularly low dose computerized tomography, offer improved diagnostic information that can optimize management and obviate unnecessary intervention.

AB - Purpose: We determined the optimal imaging study by which to diagnose and treat pregnant patients with suspected urolithiasis. Materials and Methods: A retrospective, multicenter study was performed to determine the comparative accuracy of imaging modalities used before the surgical management of suspected urolithiasis in pregnant patients. Patients with a clinical suspicion of urolithiasis were evaluated with directed imaging including renal ultrasound alone, renal ultrasound and low dose computerized tomography, or renal ultrasound and magnetic resonance urography. When indicated, patients underwent therapeutic ureteroscopy. The rate of negative ureteroscopy was determined and the positive predictive values of the imaging modalities were calculated. Results: A total of 51 pregnant patients underwent ureteroscopy. The mean age of the cohort was 27 years. Mean gestational age was 24.4 weeks. Of the women 24 (47%) underwent renal ultrasound and low dose computerized tomography, 22 (43%) underwent ultrasound alone, and 5 (10%) underwent renal ultrasound and magnetic resonance urography. Negative ureteroscopy occurred in 7 of the 51 patients (14%). The rate of negative ureteroscopy among patients who underwent renal ultrasound alone, renal ultrasound and low dose computerized tomography, and renal ultrasound and magnetic resonance urography was 23%, 4.2% and 20%, respectively. The positive predictive value of computerized tomography, magnetic resonance and ultrasound was 95.8%, 80% and 77%, respectively. Conclusions: The rate of negative ureteroscopy was 14% among pregnant women undergoing intervention in our series. Of the group treated surgically after imaging with ultrasound alone, 23% had no ureteral stone, resulting in the lowest positive predictive value of the modalities used. Alternative imaging techniques, particularly low dose computerized tomography, offer improved diagnostic information that can optimize management and obviate unnecessary intervention.

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