Primary cutaneous aspergillosis mimicking dermatophytosis

Paul Googe, S. DeCoste D: S., W. H. Herold, M. C. Mihm

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

We recently reviewed a skin biopsy specimen obtained from a child with acute monocytic leukemia that demonstrated abundant mycelia present within a keratin plug of a hair follicle, a granulomatous dermal inflammatory infiltrate, and focal dermal invasion by fungi. These histologic findings were suggestive of an invasive dermatophyte infection; however, Aspergillus flavus was identified by culture. This case illustrates the need for care in interpreting biopsy specimens of cutaneous fungal infection in the immunocompromised host, since proper treatment is determined by the specific agent present. The morphological features of fungi in tissue sections and histopathologic patterns of host response in the immunocompromised patient may be misleading in trying to identify fungal pathogens. At present, culture is the most reliable method for identifying pathogenic fungi and should be utilized to confirm appropriate therapy.

Original languageEnglish (US)
Pages (from-to)1284-1286
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume113
Issue number11
StatePublished - Jan 1 1989
Externally publishedYes

Fingerprint

Tinea
Aspergillosis
Skin
Fungi
Immunocompromised Host
Leukemia, Monocytic, Acute
Biopsy
Aspergillus flavus
Arthrodermataceae
Hair Follicle
Mycoses
Mycelium
Keratins
Therapeutics
Infection

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Googe, P., DeCoste D: S., S., Herold, W. H., & Mihm, M. C. (1989). Primary cutaneous aspergillosis mimicking dermatophytosis. Archives of Pathology and Laboratory Medicine, 113(11), 1284-1286.

Primary cutaneous aspergillosis mimicking dermatophytosis. / Googe, Paul; DeCoste D: S., S.; Herold, W. H.; Mihm, M. C.

In: Archives of Pathology and Laboratory Medicine, Vol. 113, No. 11, 01.01.1989, p. 1284-1286.

Research output: Contribution to journalArticle

Googe, P, DeCoste D: S., S, Herold, WH & Mihm, MC 1989, 'Primary cutaneous aspergillosis mimicking dermatophytosis', Archives of Pathology and Laboratory Medicine, vol. 113, no. 11, pp. 1284-1286.
Googe, Paul ; DeCoste D: S., S. ; Herold, W. H. ; Mihm, M. C. / Primary cutaneous aspergillosis mimicking dermatophytosis. In: Archives of Pathology and Laboratory Medicine. 1989 ; Vol. 113, No. 11. pp. 1284-1286.
@article{53a6edb41f0c43878ee38d21e1933418,
title = "Primary cutaneous aspergillosis mimicking dermatophytosis",
abstract = "We recently reviewed a skin biopsy specimen obtained from a child with acute monocytic leukemia that demonstrated abundant mycelia present within a keratin plug of a hair follicle, a granulomatous dermal inflammatory infiltrate, and focal dermal invasion by fungi. These histologic findings were suggestive of an invasive dermatophyte infection; however, Aspergillus flavus was identified by culture. This case illustrates the need for care in interpreting biopsy specimens of cutaneous fungal infection in the immunocompromised host, since proper treatment is determined by the specific agent present. The morphological features of fungi in tissue sections and histopathologic patterns of host response in the immunocompromised patient may be misleading in trying to identify fungal pathogens. At present, culture is the most reliable method for identifying pathogenic fungi and should be utilized to confirm appropriate therapy.",
author = "Paul Googe and {DeCoste D: S.}, S. and Herold, {W. H.} and Mihm, {M. C.}",
year = "1989",
month = "1",
day = "1",
language = "English (US)",
volume = "113",
pages = "1284--1286",
journal = "Archives of Pathology and Laboratory Medicine",
issn = "0003-9985",
publisher = "College of American Pathologists",
number = "11",

}

TY - JOUR

T1 - Primary cutaneous aspergillosis mimicking dermatophytosis

AU - Googe, Paul

AU - DeCoste D: S., S.

AU - Herold, W. H.

AU - Mihm, M. C.

PY - 1989/1/1

Y1 - 1989/1/1

N2 - We recently reviewed a skin biopsy specimen obtained from a child with acute monocytic leukemia that demonstrated abundant mycelia present within a keratin plug of a hair follicle, a granulomatous dermal inflammatory infiltrate, and focal dermal invasion by fungi. These histologic findings were suggestive of an invasive dermatophyte infection; however, Aspergillus flavus was identified by culture. This case illustrates the need for care in interpreting biopsy specimens of cutaneous fungal infection in the immunocompromised host, since proper treatment is determined by the specific agent present. The morphological features of fungi in tissue sections and histopathologic patterns of host response in the immunocompromised patient may be misleading in trying to identify fungal pathogens. At present, culture is the most reliable method for identifying pathogenic fungi and should be utilized to confirm appropriate therapy.

AB - We recently reviewed a skin biopsy specimen obtained from a child with acute monocytic leukemia that demonstrated abundant mycelia present within a keratin plug of a hair follicle, a granulomatous dermal inflammatory infiltrate, and focal dermal invasion by fungi. These histologic findings were suggestive of an invasive dermatophyte infection; however, Aspergillus flavus was identified by culture. This case illustrates the need for care in interpreting biopsy specimens of cutaneous fungal infection in the immunocompromised host, since proper treatment is determined by the specific agent present. The morphological features of fungi in tissue sections and histopathologic patterns of host response in the immunocompromised patient may be misleading in trying to identify fungal pathogens. At present, culture is the most reliable method for identifying pathogenic fungi and should be utilized to confirm appropriate therapy.

UR - http://www.scopus.com/inward/record.url?scp=0024330434&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024330434&partnerID=8YFLogxK

M3 - Article

VL - 113

SP - 1284

EP - 1286

JO - Archives of Pathology and Laboratory Medicine

JF - Archives of Pathology and Laboratory Medicine

SN - 0003-9985

IS - 11

ER -