Primary pediatric intraspinal sarcomas

Paul Klimo, Patrick J. Codd, Holcombe Grier, Liliana C. Goumnerova

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Sarcomas that arise from within the spinal canal are rare, particularly within the pediatric population. In general, these primary intraspinal sarcomas are highly aggressive, posing unique treatment challenges with respect to surgery and choice of adjuvant therapy. The goal must be to obtain the most complete resection possible to minimize the risk of recurrence and metastasis, while preventing potential neurological deficits that may result from aggressive surgery. Among these primary intraspinal sarcomas are malignant peripheral nerve sheath tumors and members of the Ewing sarcoma family of tumors. The authors present 3 cases of unique spinal sarcomas in children - 2 malignant peripheral nerve sheath tumors in patients without neurofibromatosis and an intradural extraosseous Ewing sarcoma arising from the sensory component of a lumbar spinal nerve - and discuss their management and outcome with a review of the current literature.

Original languageEnglish (US)
Pages (from-to)222-229
Number of pages8
JournalJournal of Neurosurgery: Pediatrics
Volume4
Issue number3
DOIs
StatePublished - Sep 1 2009
Externally publishedYes

Fingerprint

Sarcoma
Pediatrics
Ewing's Sarcoma
Neurilemmoma
Spinal Nerves
Neurofibromatoses
Spinal Canal
Neoplasm Metastasis
Recurrence
Therapeutics
Population
Neoplasms

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Surgery
  • Pediatrics, Perinatology, and Child Health

Cite this

Primary pediatric intraspinal sarcomas. / Klimo, Paul; Codd, Patrick J.; Grier, Holcombe; Goumnerova, Liliana C.

In: Journal of Neurosurgery: Pediatrics, Vol. 4, No. 3, 01.09.2009, p. 222-229.

Research output: Contribution to journalArticle

Klimo, Paul ; Codd, Patrick J. ; Grier, Holcombe ; Goumnerova, Liliana C. / Primary pediatric intraspinal sarcomas. In: Journal of Neurosurgery: Pediatrics. 2009 ; Vol. 4, No. 3. pp. 222-229.
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