Primary subretinal abscess caused by acanthamoeba

Clinical and pathologic case report and review of the literature

Nicholas Anderson, Sarah E. Hamler, Lisa Duncan

Research output: Contribution to journalReview article

Abstract

Purpose: To report the clinical and pathologic findings in a patient with a primary Acanthamoeba subretinal abscess. Methods: A healthy 40-year-old man was evaluated and treated for a subretinal abscess. A subretinal aspirate was evaluated using hematoxylin-eosin stains and polymerase chain reaction. Results: Results of the histologic examination of the subretinal aspirate demonstrated numerous Acanthamoeba cysts. The diagnosis was confirmed by polymerase chain reaction. The infection was treated with local and systemic antimicrobials. The visual acuity remained stable, and there was no local or systemic spread of the infection. Conclusion: To the authors' knowledge, this is the first biopsy-proven case of primary subretinal abscess because of Acanthamoeba. Acanthamoeba should be considered in the differential diagnosis of a subretinal abscess, even in the absence of systemic or corneal symptoms. Aggressive treatment can prevent serious ocular and systemic complications.

Original languageEnglish (US)
Pages (from-to)37-39
Number of pages3
JournalRetinal Cases and Brief Reports
Volume6
Issue number1
DOIs
StatePublished - Dec 2012

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Acanthamoeba
Abscess
Polymerase Chain Reaction
Hematoxylin
Eosine Yellowish-(YS)
Infection
Visual Acuity
Cysts
Differential Diagnosis
Coloring Agents
Biopsy

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

Primary subretinal abscess caused by acanthamoeba : Clinical and pathologic case report and review of the literature. / Anderson, Nicholas; Hamler, Sarah E.; Duncan, Lisa.

In: Retinal Cases and Brief Reports, Vol. 6, No. 1, 12.2012, p. 37-39.

Research output: Contribution to journalReview article

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