Prognostic nutritional index in relation to hospital stay in women with gynecologic cancer

Joseph Santoso, Todd Canada, Bernadette Latson, Kalyani Alladi, Joseph A. Lucci, Robert L. Coleman

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Objective: To estimate the prevalence of malnutrition, correlate it with length of hospital stay, and evaluate laboratory tools to define it in gynecologic oncology. Methods: Sixty-seven consecutive hospitalized gynecologic oncology patients were evaluated prospectively using the standardized Prognostic Nutritional Index method, based on serum albumin, transferrin, triceps skin fold and skin sensitivity tests, which defines criteria for malnourished and nourished patients. It was correlated with length of hospital stay. The Mann-Whitney test and Pearson's correlation coefficient were used to evaluate statistical relationships. Results: Cancer distribution among study subjects was 39 cervical (58%), 16 uterine (24%), 11 ovarian (16%), and one vulvar (2%). Malnutrition was found in 36 of 67 women (54%; 95% confidence interval [CI] 41%, 66%). The median (interquartile range) hospital stays of nourished women (n = 31) and malnourished women (n = 36) were 6 (range 4-7) days and 8 (range 6-16) days, respectively (two-sided P = .004). That difference remained after controlling for age, extent of metastases, and cancer sites. Albumin correlated well with Prognostic Nutritional Index (R = -.78; 95% CI -.86, -.66; P < .001). Albumin also correlated with length of hospital stay R = -.41; 95% CI -.56, -.25; P < .001). Conclusion: Malnutrition is common in gynecologic oncology patients and contributes to longer hospital stays. Albumin is a good substitute for the Prognostic Nutritional Index laboratory test for assessing malnutrition.

Original languageEnglish (US)
Article number11828
Pages (from-to)844-846
Number of pages3
JournalObstetrics and gynecology
Volume95
Issue number6
DOIs
StatePublished - Jan 1 2000

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Nutrition Assessment
Length of Stay
Malnutrition
Neoplasms
Albumins
Confidence Intervals
Transferrin
Skin Tests
Serum Albumin
Neoplasm Metastasis
Skin

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

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Prognostic nutritional index in relation to hospital stay in women with gynecologic cancer. / Santoso, Joseph; Canada, Todd; Latson, Bernadette; Alladi, Kalyani; Lucci, Joseph A.; Coleman, Robert L.

In: Obstetrics and gynecology, Vol. 95, No. 6, 11828, 01.01.2000, p. 844-846.

Research output: Contribution to journalArticle

Santoso, Joseph ; Canada, Todd ; Latson, Bernadette ; Alladi, Kalyani ; Lucci, Joseph A. ; Coleman, Robert L. / Prognostic nutritional index in relation to hospital stay in women with gynecologic cancer. In: Obstetrics and gynecology. 2000 ; Vol. 95, No. 6. pp. 844-846.
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abstract = "Objective: To estimate the prevalence of malnutrition, correlate it with length of hospital stay, and evaluate laboratory tools to define it in gynecologic oncology. Methods: Sixty-seven consecutive hospitalized gynecologic oncology patients were evaluated prospectively using the standardized Prognostic Nutritional Index method, based on serum albumin, transferrin, triceps skin fold and skin sensitivity tests, which defines criteria for malnourished and nourished patients. It was correlated with length of hospital stay. The Mann-Whitney test and Pearson's correlation coefficient were used to evaluate statistical relationships. Results: Cancer distribution among study subjects was 39 cervical (58{\%}), 16 uterine (24{\%}), 11 ovarian (16{\%}), and one vulvar (2{\%}). Malnutrition was found in 36 of 67 women (54{\%}; 95{\%} confidence interval [CI] 41{\%}, 66{\%}). The median (interquartile range) hospital stays of nourished women (n = 31) and malnourished women (n = 36) were 6 (range 4-7) days and 8 (range 6-16) days, respectively (two-sided P = .004). That difference remained after controlling for age, extent of metastases, and cancer sites. Albumin correlated well with Prognostic Nutritional Index (R = -.78; 95{\%} CI -.86, -.66; P < .001). Albumin also correlated with length of hospital stay R = -.41; 95{\%} CI -.56, -.25; P < .001). Conclusion: Malnutrition is common in gynecologic oncology patients and contributes to longer hospital stays. Albumin is a good substitute for the Prognostic Nutritional Index laboratory test for assessing malnutrition.",
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