Progress in the development of effective vaccines to prevent selected gram-positive bacterial infections

Michael S. Bronze, James Dale

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Infections caused by virulent Gram-positive bacteria, such as Staphylococcus aureus, group B streptococci and group A streptococci, remain significant causes of morbidity and mortality despite progress in antimicrobial therapy. Despite significant advances in the understanding of the pathogenesis of infection caused by these organisms, there are only limited strategies to prevent infection. In this article, we review efforts to develop safe and effective vaccines that would prevent infections caused by these 3 pathogens.

Original languageEnglish (US)
Pages (from-to)218-225
Number of pages8
JournalAmerican Journal of the Medical Sciences
Volume340
Issue number3
DOIs
StatePublished - Jan 1 2010

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Gram-Positive Bacterial Infections
Vaccines
Infection
Streptococcus pyogenes
Gram-Positive Bacteria
Streptococcus
Staphylococcus aureus
Morbidity
Mortality

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Progress in the development of effective vaccines to prevent selected gram-positive bacterial infections. / Bronze, Michael S.; Dale, James.

In: American Journal of the Medical Sciences, Vol. 340, No. 3, 01.01.2010, p. 218-225.

Research output: Contribution to journalArticle

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