Protein-RNA contacts in Sendai virus nucleocapsids revealed by photo-crosslinking

Rajendra Raghow, David W. Kingsbury

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Contacts between protein species and nucleic acid bases in the genomic RNA of Sendai virus nucleocapsids were examined by ultraviolet light (uv)-induced crosslinking. Both NP, the nucleocapsid structure unit, and P, the less abundant protein species implicated in viral transcription, were efficiently linked to the RNA, indicating that both species contact RNA bases. However, the RNA serves as template for viral RNA polymerases in the intact nucleocapsid, so these contacts must either be reversible or restricted to noncoding regions of the bases.

Original languageEnglish (US)
Pages (from-to)267-271
Number of pages5
JournalVirology
Volume98
Issue number1
DOIs
StatePublished - Oct 15 1979

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Sendai virus
Nucleocapsid
RNA
Proteins
RNA Viruses
Viral RNA
DNA-Directed RNA Polymerases
Ultraviolet Rays
Nucleic Acids

All Science Journal Classification (ASJC) codes

  • Virology

Cite this

Protein-RNA contacts in Sendai virus nucleocapsids revealed by photo-crosslinking. / Raghow, Rajendra; Kingsbury, David W.

In: Virology, Vol. 98, No. 1, 15.10.1979, p. 267-271.

Research output: Contribution to journalArticle

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