Proteome analysis by two-dimensional gel electrophoresis and mass spectrometry

Strengths and limitations

Research output: Contribution to journalReview article

129 Citations (Scopus)

Abstract

Two-dimensional gel electrophoresis, mass spectrometry and bioinformatics are the key components of current proteomics technology. The purpose of this review is to give an overview of the basic concepts of 2DE-based proteomics methodology, to discuss the advantages and limitations of the approach, and to highlight some recent advancements in 2DE-based technology.

Original languageEnglish (US)
Pages (from-to)273-281
Number of pages9
JournalTrAC - Trends in Analytical Chemistry
Volume22
Issue number5
DOIs
StatePublished - May 1 2003

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Proteome
Electrophoresis
Mass spectrometry
Gels
Bioinformatics
Proteomics

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Spectroscopy

Cite this

Proteome analysis by two-dimensional gel electrophoresis and mass spectrometry : Strengths and limitations. / Beranova, Sarka.

In: TrAC - Trends in Analytical Chemistry, Vol. 22, No. 5, 01.05.2003, p. 273-281.

Research output: Contribution to journalReview article

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