Proteomics of the human pituitary tissue

Bioanalytical methods and applications

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

The pituitary is the central endocrine gland that plays complex regulatory roles in growth, reproduction and metabolism of the body. The human pituitary tissue proteome has been the target of a number of investigations that applied various combinations of advanced separation techniques, mass spectrometry, and bioinformatics tools. This review describes the main features of the bioanalytical workflows used in pituitary proteomics, and summarizes major applications in pituitary proteome mapping, differential protein expression profiling in health and disease, and discovery of post-translational modifications in pituitary proteins.

Original languageEnglish (US)
Pages (from-to)1989-2003
Number of pages15
JournalBioanalysis
Volume6
Issue number14
DOIs
StatePublished - 2014

Fingerprint

Proteome
Proteomics
Tissue
Endocrine Glands
Workflow
Post Translational Protein Processing
Bioinformatics
Computational Biology
Metabolism
Reproduction
Mass spectrometry
Mass Spectrometry
Proteins
Health
Growth

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Medical Laboratory Technology
  • Analytical Chemistry
  • Medicine(all)

Cite this

Proteomics of the human pituitary tissue : Bioanalytical methods and applications. / Giorgianni, Francesco; Koirala, Diwa; Beranova, Sarka.

In: Bioanalysis, Vol. 6, No. 14, 2014, p. 1989-2003.

Research output: Contribution to journalReview article

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