Psychiatric agents and implications for perioperative analgesia

Blas Catalani, Craig S. Hamilton, Edwin W. Herron, Richard D. Urman, Charles J. Fox, Alan David Kaye

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

The use of antidepressants, anxiolytics, mood stabilizers, anticonvulsants, and major tranquilizers introduces neurochemical, behavioral, cognitive, and emotional factors that increase the complexity of medical and surgical tasks. Increasingly, various classes of psychotropic medications are being prescribed in the perioperative setting for their analgesic properties in patients with or without a psychiatric diagnosis. In many cases, the precise mechanisms of action and dose-response relationships by which these agents mediate analgesia are largely unclear. An appreciation of the side effects and adverse-effect profiles of such medications and familiarity with the clinically relevant drug interactions that may occur in the perioperative setting are imperative to ensure the best possible outcome in dealing with patients on these medications. This review focuses on various classes of psychotropic agents, which are addressed individually, with particular focus on their analgesic properties. The latest published research is summarized, deficiencies in our current collective knowledge are discussed, and evidence-based recommendations are made for clinical practice.

Original languageEnglish (US)
Pages (from-to)167-181
Number of pages15
JournalBest Practice and Research: Clinical Anaesthesiology
Volume28
Issue number2
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

Fingerprint

Analgesia
Psychiatry
Analgesics
Anti-Anxiety Agents
Drug Interactions
Mental Disorders
Anticonvulsants
Antidepressive Agents
Antipsychotic Agents
Research
Recognition (Psychology)

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

Cite this

Psychiatric agents and implications for perioperative analgesia. / Catalani, Blas; Hamilton, Craig S.; Herron, Edwin W.; Urman, Richard D.; Fox, Charles J.; Kaye, Alan David.

In: Best Practice and Research: Clinical Anaesthesiology, Vol. 28, No. 2, 01.01.2014, p. 167-181.

Research output: Contribution to journalReview article

Catalani, Blas ; Hamilton, Craig S. ; Herron, Edwin W. ; Urman, Richard D. ; Fox, Charles J. ; Kaye, Alan David. / Psychiatric agents and implications for perioperative analgesia. In: Best Practice and Research: Clinical Anaesthesiology. 2014 ; Vol. 28, No. 2. pp. 167-181.
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