Pulp and Dentin Regeneration

Misako Nakashima, George Huang

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Citations (Scopus)

Abstract

This chapter describes recent advances and promising approaches for pulp and dentin regeneration, including the concept of revitalization, harnessing stem and progenitor cells and/or morphogenic signaling molecules in addition to extracellular matrix scaffold for partial and de novo (complete) regeneration of pulp with newly deposited regenerated dentin-like tissues. Intervention in the progressive tooth structure damage via pulp-dentin regeneration can delay or prevent tooth loss. In the ectopic pulp and dentin regeneration in the subcutaneous space, no nerve fibers were detectable by staining. Intervention in the progressive tooth structure damage via pulp-dentin regeneration can delay or prevent tooth loss. Before complete pulp necrosis, the remaining pulp tissue may be recovered after disinfection. To induce regeneration, engineered pulp tissues may be inserted into the pulp space to facilitate the entire recovery of pulp tissue and the generation of new dentin.

Original languageEnglish (US)
Title of host publicationStem Cells in Craniofacial Development and Regeneration
PublisherJohn Wiley and Sons
Pages461-484
Number of pages24
ISBN (Print)9781118279236
DOIs
StatePublished - Mar 26 2013

Fingerprint

Dentin
Pulp
Regeneration
Tooth Loss
Tissue
Tooth
Dental Pulp Necrosis
Stem Cells
Disinfection
Nerve Fibers
Extracellular Matrix
Staining and Labeling
Scaffolds
Recovery
Molecules
Fibers

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Nakashima, M., & Huang, G. (2013). Pulp and Dentin Regeneration. In Stem Cells in Craniofacial Development and Regeneration (pp. 461-484). John Wiley and Sons. https://doi.org/10.1002/9781118498026.ch26

Pulp and Dentin Regeneration. / Nakashima, Misako; Huang, George.

Stem Cells in Craniofacial Development and Regeneration. John Wiley and Sons, 2013. p. 461-484.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nakashima, M & Huang, G 2013, Pulp and Dentin Regeneration. in Stem Cells in Craniofacial Development and Regeneration. John Wiley and Sons, pp. 461-484. https://doi.org/10.1002/9781118498026.ch26
Nakashima M, Huang G. Pulp and Dentin Regeneration. In Stem Cells in Craniofacial Development and Regeneration. John Wiley and Sons. 2013. p. 461-484 https://doi.org/10.1002/9781118498026.ch26
Nakashima, Misako ; Huang, George. / Pulp and Dentin Regeneration. Stem Cells in Craniofacial Development and Regeneration. John Wiley and Sons, 2013. pp. 461-484
@inbook{e553e579197844fc9386685a16147d49,
title = "Pulp and Dentin Regeneration",
abstract = "This chapter describes recent advances and promising approaches for pulp and dentin regeneration, including the concept of revitalization, harnessing stem and progenitor cells and/or morphogenic signaling molecules in addition to extracellular matrix scaffold for partial and de novo (complete) regeneration of pulp with newly deposited regenerated dentin-like tissues. Intervention in the progressive tooth structure damage via pulp-dentin regeneration can delay or prevent tooth loss. In the ectopic pulp and dentin regeneration in the subcutaneous space, no nerve fibers were detectable by staining. Intervention in the progressive tooth structure damage via pulp-dentin regeneration can delay or prevent tooth loss. Before complete pulp necrosis, the remaining pulp tissue may be recovered after disinfection. To induce regeneration, engineered pulp tissues may be inserted into the pulp space to facilitate the entire recovery of pulp tissue and the generation of new dentin.",
author = "Misako Nakashima and George Huang",
year = "2013",
month = "3",
day = "26",
doi = "10.1002/9781118498026.ch26",
language = "English (US)",
isbn = "9781118279236",
pages = "461--484",
booktitle = "Stem Cells in Craniofacial Development and Regeneration",
publisher = "John Wiley and Sons",

}

TY - CHAP

T1 - Pulp and Dentin Regeneration

AU - Nakashima, Misako

AU - Huang, George

PY - 2013/3/26

Y1 - 2013/3/26

N2 - This chapter describes recent advances and promising approaches for pulp and dentin regeneration, including the concept of revitalization, harnessing stem and progenitor cells and/or morphogenic signaling molecules in addition to extracellular matrix scaffold for partial and de novo (complete) regeneration of pulp with newly deposited regenerated dentin-like tissues. Intervention in the progressive tooth structure damage via pulp-dentin regeneration can delay or prevent tooth loss. In the ectopic pulp and dentin regeneration in the subcutaneous space, no nerve fibers were detectable by staining. Intervention in the progressive tooth structure damage via pulp-dentin regeneration can delay or prevent tooth loss. Before complete pulp necrosis, the remaining pulp tissue may be recovered after disinfection. To induce regeneration, engineered pulp tissues may be inserted into the pulp space to facilitate the entire recovery of pulp tissue and the generation of new dentin.

AB - This chapter describes recent advances and promising approaches for pulp and dentin regeneration, including the concept of revitalization, harnessing stem and progenitor cells and/or morphogenic signaling molecules in addition to extracellular matrix scaffold for partial and de novo (complete) regeneration of pulp with newly deposited regenerated dentin-like tissues. Intervention in the progressive tooth structure damage via pulp-dentin regeneration can delay or prevent tooth loss. In the ectopic pulp and dentin regeneration in the subcutaneous space, no nerve fibers were detectable by staining. Intervention in the progressive tooth structure damage via pulp-dentin regeneration can delay or prevent tooth loss. Before complete pulp necrosis, the remaining pulp tissue may be recovered after disinfection. To induce regeneration, engineered pulp tissues may be inserted into the pulp space to facilitate the entire recovery of pulp tissue and the generation of new dentin.

UR - http://www.scopus.com/inward/record.url?scp=84887222090&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84887222090&partnerID=8YFLogxK

U2 - 10.1002/9781118498026.ch26

DO - 10.1002/9781118498026.ch26

M3 - Chapter

AN - SCOPUS:84887222090

SN - 9781118279236

SP - 461

EP - 484

BT - Stem Cells in Craniofacial Development and Regeneration

PB - John Wiley and Sons

ER -