Pyloric stenosis

an enigma more than a century after the first successful treatment

Yousef El-Gohary, Abdelhafeez Abdelhafeez, Elizabeth Paton, Ankush Gosain, Andrew J. Murphy

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Despite hypertrophic pyloric stenosis (HPS) being one of the most frequently treated pediatric surgical conditions, its etiology remains incompletely understood. We review the diagnosis and treatment of this condition with an emphasis on the evolution of surgical techniques that led to laparoscopic pyloromyotomy, the most frequently performed technique for HPS today. In addition, we review key developments in the understanding of HPS etiology and treatment, including the postulated etiology of work-induced hypertrophy of the pylorus, its association with prokinetic macrolide antibiotics, and the emerging role of atropine sulfate as a medical treatment for HPS or a rescue treatment for incomplete myotomy.

Original languageEnglish (US)
Pages (from-to)21-27
Number of pages7
JournalPediatric Surgery International
Volume34
Issue number1
DOIs
StatePublished - Jan 1 2018

Fingerprint

Hypertrophic Pyloric Stenosis
Pyloric Stenosis
Pylorus
Macrolides
Atropine
Hypertrophy
Pediatrics
Anti-Bacterial Agents

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

Pyloric stenosis : an enigma more than a century after the first successful treatment. / El-Gohary, Yousef; Abdelhafeez, Abdelhafeez; Paton, Elizabeth; Gosain, Ankush; Murphy, Andrew J.

In: Pediatric Surgery International, Vol. 34, No. 1, 01.01.2018, p. 21-27.

Research output: Contribution to journalReview article

El-Gohary, Yousef ; Abdelhafeez, Abdelhafeez ; Paton, Elizabeth ; Gosain, Ankush ; Murphy, Andrew J. / Pyloric stenosis : an enigma more than a century after the first successful treatment. In: Pediatric Surgery International. 2018 ; Vol. 34, No. 1. pp. 21-27.
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