QDR 4500A DXA overestimates fat-free mass compared with criterion methods

Frances Tylavsky, Timothy Lohman, Barbara A. Blunt, Dale A. Schoeller, Thomas Fuerst, Jane A. Cauley, Michael C. Nevitt, Marjolein Visser, Tamara B. Harris

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Abstract

This study evaluated the accuracy with which the dual-energy X-ray absorptiometer (Hologic QDR 4500A) measured fat-free mass (FFM), fat mass (FM), and hydration of FFM. In a study of 58 men and women (ages 70-79 yr), the QDR 4500A was found to provide a systematically higher estimate of FFM and lower estimate of FM than a four-component model of body composition. A correction factor from this study was developed and applied to two other samples (n = 13 and 37). We found mean corrected levels of FFM and FM to be equivalent to that obtained by the four-component model or total body water. In addition, the hydration of the corrected FFM was closer to the established hydration level in adult samples and that obtained from the four-component model. These findings suggest that the current calibration of the fan-beam system of the Hologic QDR 4500A provides an overestimate of FFM and underestimate of FM compared with reference methods.

Original languageEnglish (US)
Pages (from-to)959-965
Number of pages7
JournalJournal of applied physiology
Volume94
Issue number3
DOIs
StatePublished - Mar 1 2003

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Fats
Body Water
Body Composition
Calibration
X-Rays

All Science Journal Classification (ASJC) codes

  • Physiology
  • Physiology (medical)

Cite this

Tylavsky, F., Lohman, T., Blunt, B. A., Schoeller, D. A., Fuerst, T., Cauley, J. A., ... Harris, T. B. (2003). QDR 4500A DXA overestimates fat-free mass compared with criterion methods. Journal of applied physiology, 94(3), 959-965. https://doi.org/10.1152/japplphysiol.00732.2002

QDR 4500A DXA overestimates fat-free mass compared with criterion methods. / Tylavsky, Frances; Lohman, Timothy; Blunt, Barbara A.; Schoeller, Dale A.; Fuerst, Thomas; Cauley, Jane A.; Nevitt, Michael C.; Visser, Marjolein; Harris, Tamara B.

In: Journal of applied physiology, Vol. 94, No. 3, 01.03.2003, p. 959-965.

Research output: Contribution to journalArticle

Tylavsky, F, Lohman, T, Blunt, BA, Schoeller, DA, Fuerst, T, Cauley, JA, Nevitt, MC, Visser, M & Harris, TB 2003, 'QDR 4500A DXA overestimates fat-free mass compared with criterion methods', Journal of applied physiology, vol. 94, no. 3, pp. 959-965. https://doi.org/10.1152/japplphysiol.00732.2002
Tylavsky, Frances ; Lohman, Timothy ; Blunt, Barbara A. ; Schoeller, Dale A. ; Fuerst, Thomas ; Cauley, Jane A. ; Nevitt, Michael C. ; Visser, Marjolein ; Harris, Tamara B. / QDR 4500A DXA overestimates fat-free mass compared with criterion methods. In: Journal of applied physiology. 2003 ; Vol. 94, No. 3. pp. 959-965.
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