Radiation-associated meningioma in the elderly: Development of meningioma with olfactory neuroblastoma recurrence 10 years after irradiation

Mahlon Johnson, Kenneth Piech, Seyed Emandian

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The pathogenesis of meningiomas is not established [1,2]. However, intracranial irradiation in childhood is a risk factor for the development of meningiomas later in life [2-6]. Children treated with irradiation for tinea capitis of the scalp showed an almost ten-fold increase in development of meningiomas relative to age -matched controls [2,3]. In a study of almost 18,000 children who survived for at least five years after receiving external beam radiation, 2.3% developed meningiomas within 17 years of follow-up [5]. Notably, meningioma formation after radiation therapy (RT) occurs almost exclusively in patients irradiated as children or young adults. Development of a radiation-associated meningioma (RAM) in patients who received RT in the sixth or seventh decade is very rare. For example, in studies including a total of 58 adults receiving RT, only two cases of RAM occurred in patients 50 years old or older [8,9].

Original languageEnglish (US)
Pages (from-to)460-463
Number of pages4
JournalAnnals of Clinical and Laboratory Science
Volume43
Issue number4
StatePublished - Dec 9 2013
Externally publishedYes

Fingerprint

Olfactory Esthesioneuroblastoma
Radiotherapy
Meningioma
Irradiation
Radiation
Recurrence
Tinea Capitis
Scalp
Young Adult

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Microbiology
  • Pathology and Forensic Medicine
  • Immunology
  • Hematology
  • Molecular Biology
  • Clinical Biochemistry
  • Medical Laboratory Technology

Cite this

Radiation-associated meningioma in the elderly : Development of meningioma with olfactory neuroblastoma recurrence 10 years after irradiation. / Johnson, Mahlon; Piech, Kenneth; Emandian, Seyed.

In: Annals of Clinical and Laboratory Science, Vol. 43, No. 4, 09.12.2013, p. 460-463.

Research output: Contribution to journalArticle

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