RAS and connective tissue in the heart

Research output: Contribution to journalReview article

31 Citations (Scopus)

Abstract

Circulating angiotensin (Ang) II has well-known endocrine properties in the cardiovasculature. AngII, produced de novo within the heart, has various autocrine and paracrine properties on resident cells expressed via AT1 receptor-ligand binding. Herein, we review the heart's renin-angiotensin system and its role in connective tissue turnover involving heart valve leaflets and fibrous tissue that appears at sites of injury, such as following myocardial infarction.

Original languageEnglish (US)
Pages (from-to)919-931
Number of pages13
JournalInternational Journal of Biochemistry and Cell Biology
Volume35
Issue number6
DOIs
StatePublished - Jun 1 2003

Fingerprint

Connective Tissue
Tissue
Heart Valves
Renin-Angiotensin System
Angiotensin II
Myocardial Infarction
Angiotensins
Ligands
Renin
Wounds and Injuries

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Cell Biology

Cite this

RAS and connective tissue in the heart. / Sun, Yao; Weber, Karl.

In: International Journal of Biochemistry and Cell Biology, Vol. 35, No. 6, 01.06.2003, p. 919-931.

Research output: Contribution to journalReview article

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