Recurrent abruptio placentae in a cynomolgus monkey (Macaca fascicularis)

N. Schlabritz-Loutsevitch, G. Hubbard, Jie Zhang, S. Gupta, E. Dick

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Introduction: Abruptio placentae, defined as premature separation of a normally implanted placenta, is a life threatening pregnancy complication with unknown pathophysiology. A history of abruptio placentae is the major risk factor for this pregnancy complication in humans. We describe the first case of recurrent abruptio placentae in a Macaca fascicularis. Material and methods: A pregnant M. fascicularis at term gestation was presented with weakness and hypothermia. Cesarean section revealed retroplacental hemorrhage with partial placental separation from the uterus. Results: The weight of the female fetus was within the lower birth weight range for these species. The maternal side of placenta contained necrotic tissue, occupying approximately 60% of the maternal surface. The placental implantation bed demonstrated neutrophil infiltration. Perivascular collections of lymphocytes were noticed in the uterine smooth muscle. Conclusion: This case report underlines the importance of neutrophil infiltration and uterine venous drainage in the cascade of events leading to abruptio placentae.

Original languageEnglish (US)
Pages (from-to)388-390
Number of pages3
JournalPlacenta
Volume34
Issue number4
DOIs
StatePublished - Apr 1 2013

Fingerprint

Abruptio Placentae
Macaca fascicularis
Pregnancy Complications
Neutrophil Infiltration
Placenta
Mothers
Myometrium
Hypothermia
Birth Weight
Cesarean Section
Uterus
Smooth Muscle
Drainage
Fetus
Lymphocytes
Hemorrhage
Weights and Measures
Pregnancy

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology
  • Developmental Biology

Cite this

Recurrent abruptio placentae in a cynomolgus monkey (Macaca fascicularis). / Schlabritz-Loutsevitch, N.; Hubbard, G.; Zhang, Jie; Gupta, S.; Dick, E.

In: Placenta, Vol. 34, No. 4, 01.04.2013, p. 388-390.

Research output: Contribution to journalArticle

Schlabritz-Loutsevitch, N, Hubbard, G, Zhang, J, Gupta, S & Dick, E 2013, 'Recurrent abruptio placentae in a cynomolgus monkey (Macaca fascicularis)', Placenta, vol. 34, no. 4, pp. 388-390. https://doi.org/10.1016/j.placenta.2013.01.007
Schlabritz-Loutsevitch, N. ; Hubbard, G. ; Zhang, Jie ; Gupta, S. ; Dick, E. / Recurrent abruptio placentae in a cynomolgus monkey (Macaca fascicularis). In: Placenta. 2013 ; Vol. 34, No. 4. pp. 388-390.
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