Regression of a congenital mesoblastic nephroma

Sarah Whittle, Ankush Gosain, Petagay Y. Scott Brown, Lairsa Debelenko, Susana Raimondi, Judith A. Wilimas, Jesse J. Jenkins, Andrew M. Davidoff

Research output: Contribution to journalArticle

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Abstract

Histologically, the cellular variant of congenital mesoblastic nephroma (CMN) is very similar to another rare tumor of infancy, infantile fibrosarcoma (IFS). In addition to the histologic similarities, these tumor types share cytogenetic abnormalities including translocation t(12;15)(p13;q25). We describe herein the case of a child who did not have immediate surgical resection of a CMN and whose tumor was untreated for 8 months. During that time, the tumor demonstrated a significant degree of regression. The shared translocation with IFS, a tumor with well-documented potential for spontaneous regression, suggests that this genetic abnormality may have contributed to the favorable clinical course.

Original languageEnglish (US)
Pages (from-to)364-368
Number of pages5
JournalPediatric Blood and Cancer
Volume55
Issue number2
DOIs
StatePublished - Aug 1 2010

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Mesoblastic Nephroma
Fibrosarcoma
Neoplasms
Chromosome Aberrations

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

Cite this

Whittle, S., Gosain, A., Scott Brown, P. Y., Debelenko, L., Raimondi, S., Wilimas, J. A., ... Davidoff, A. M. (2010). Regression of a congenital mesoblastic nephroma. Pediatric Blood and Cancer, 55(2), 364-368. https://doi.org/10.1002/pbc.22486

Regression of a congenital mesoblastic nephroma. / Whittle, Sarah; Gosain, Ankush; Scott Brown, Petagay Y.; Debelenko, Lairsa; Raimondi, Susana; Wilimas, Judith A.; Jenkins, Jesse J.; Davidoff, Andrew M.

In: Pediatric Blood and Cancer, Vol. 55, No. 2, 01.08.2010, p. 364-368.

Research output: Contribution to journalArticle

Whittle, S, Gosain, A, Scott Brown, PY, Debelenko, L, Raimondi, S, Wilimas, JA, Jenkins, JJ & Davidoff, AM 2010, 'Regression of a congenital mesoblastic nephroma', Pediatric Blood and Cancer, vol. 55, no. 2, pp. 364-368. https://doi.org/10.1002/pbc.22486
Whittle S, Gosain A, Scott Brown PY, Debelenko L, Raimondi S, Wilimas JA et al. Regression of a congenital mesoblastic nephroma. Pediatric Blood and Cancer. 2010 Aug 1;55(2):364-368. https://doi.org/10.1002/pbc.22486
Whittle, Sarah ; Gosain, Ankush ; Scott Brown, Petagay Y. ; Debelenko, Lairsa ; Raimondi, Susana ; Wilimas, Judith A. ; Jenkins, Jesse J. ; Davidoff, Andrew M. / Regression of a congenital mesoblastic nephroma. In: Pediatric Blood and Cancer. 2010 ; Vol. 55, No. 2. pp. 364-368.
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