Regression of Calcium Channel Blocker--Induced Gingival Enlargement in the Absence of Periodontal Therapy

Rania Livada, Wes Shelton, Paul Bland, Jacob Shiloal

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

AIM: To illustrate the negative effect of calcium channel blocker (CCB) drugs on the gingival tissues and the reversibility of these lesions.

CASE DESCRIPTION: The authors examined a forty-eight year-old male patient with drug-induced gingival enlargement associated with diltiazem, a CCB drug. Prior to initiating the proposed periodontal treatment, the patient was advised to consult his physician, for a possible switch to a different anti-hypertensive drug. The patient returned to the clinic three months later with a significant regression of the gingival overgrowth, which was induced by the patient ceasing the prescribed regimen without medical consultation or periodontal intervention.

CONCLUSION: Although CCBs are effective cardiovascular drugs, they can negatively impact the oral health by promoting gingival overgrowth in some patients. Substitution of these drugs is strongly recommended prior to any periodontal intervention in order to improve prognosis and prevent recurrence, and should be done only by the medical providers.

Original languageEnglish (US)
JournalThe Journal of the Tennessee Dental Association
Volume95
Issue number2
StatePublished - Sep 1 2015

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Calcium Channel Blockers
Gingival Overgrowth
Pharmaceutical Preparations
Drug Substitution
Therapeutics
Cardiovascular Agents
Diltiazem
Oral Health
Antihypertensive Agents
Referral and Consultation
Physicians
Recurrence

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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Regression of Calcium Channel Blocker--Induced Gingival Enlargement in the Absence of Periodontal Therapy. / Livada, Rania; Shelton, Wes; Bland, Paul; Shiloal, Jacob.

In: The Journal of the Tennessee Dental Association, Vol. 95, No. 2, 01.09.2015.

Research output: Contribution to journalArticle

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