Abstract

Established cardiac fibrosis (ECF) with symptomatic heart failure preserved ejection fraction represents an ever-increasing segment of the hypertensive population. The regression of ECF with attendant improvement in myocardial stiffness and symptomatic failure represents an unmet health care need. Is the regression of ECF in hypertensive heart disease feasible and will stiffness and symptomatic failure be improved? What is the cellular/molecular signaling involved in its regression? What incremental knowledge is needed to proceed effectively? These issues are addressed in this Review.

Original languageEnglish (US)
Pages (from-to)1049-1052
Number of pages4
JournalAmerican Journal of Hypertension
Volume30
Issue number11
DOIs
StatePublished - Nov 1 2017

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Heart Diseases
Fibrosis
Heart Failure
Delivery of Health Care
Population

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Regression of Established Cardiac Fibrosis in Hypertensive Heart Disease. / Weber, Karl; Sun, Yao; Gerling, Ivan; Guntaka, Ramareddy.

In: American Journal of Hypertension, Vol. 30, No. 11, 01.11.2017, p. 1049-1052.

Research output: Contribution to journalReview article

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