Renal artery Doppler investigation of the etiology of oligohydramnios in postterm pregnancy

A. U. Oz, B. Holub, I. Mendilcioglu, Giancarlo Mari, R. O. Bahado-Singh

Research output: Contribution to journalArticle

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Abstract

OBJECTIVE: To investigate the etiology of oligohydramnios in postterm pregnancy using Doppler velocimetry. METHODS: Renal and umbilical artery Doppler velocimetry were performed in women with singleton postterm (287 days' or more gestation) pregnancies. The renal and umbilical artery Doppler resistance index (RI) and end-diastolic velocity were measured. Stepwise logistic regression and the two-tailed t test were used to determine whether the Doppler indices correlated with oligohydramnios (amniotic fluid index less than 5 cm). RESULTS: We studied 147 well-dated, singleton, postterm pregnancies, of which 21 (14.3%) had oligohydramnios. For the study cohort, the mean (±standard deviation) gestational age at Doppler was 41.4 ± 0.45 weeks and at delivery 41.8 ± 0.47 weeks. Stepwise logistic regression using renal and umbilical artery Doppler indices found the renal RI to be the only significant predictor of oligohydramnios: β = -10.4186, P < .05 (odds ratio [95% confidence interval (CI)] = 0, 0.88). The renal artery RI was significantly higher in cases with oligohydramnios (RI: mean (±standard error) = 0.8843 ± 0.11 versus 0.8601 ± 0.05, P ≤ 0.05). A renal artery Doppler end-diastolic velocity below the mean for gestation significantly increased the risk of oligohydramnios: relative risk (95% CI), 1.5 (1.1, 2.0). CONCLUSION: Renal artery Doppler was more predictive of oligohydramnios than the umbilical RI. The reduced renal artery end-diastolic velocity suggests that increased arterial impedance is an important factor in the development of oligohydramnios in prolonged pregnancies.

Original languageEnglish (US)
Pages (from-to)715-718
Number of pages4
JournalObstetrics and Gynecology
Volume100
Issue number4
DOIs
StatePublished - Oct 1 2002
Externally publishedYes

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Oligohydramnios
Renal Artery
Pregnancy
Umbilical Arteries
Rheology
Logistic Models
Prolonged Pregnancy
Confidence Intervals
Umbilicus
Amniotic Fluid
Electric Impedance
Gestational Age
Cohort Studies
Odds Ratio
Kidney

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

Cite this

Renal artery Doppler investigation of the etiology of oligohydramnios in postterm pregnancy. / Oz, A. U.; Holub, B.; Mendilcioglu, I.; Mari, Giancarlo; Bahado-Singh, R. O.

In: Obstetrics and Gynecology, Vol. 100, No. 4, 01.10.2002, p. 715-718.

Research output: Contribution to journalArticle

Oz, A. U. ; Holub, B. ; Mendilcioglu, I. ; Mari, Giancarlo ; Bahado-Singh, R. O. / Renal artery Doppler investigation of the etiology of oligohydramnios in postterm pregnancy. In: Obstetrics and Gynecology. 2002 ; Vol. 100, No. 4. pp. 715-718.
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abstract = "OBJECTIVE: To investigate the etiology of oligohydramnios in postterm pregnancy using Doppler velocimetry. METHODS: Renal and umbilical artery Doppler velocimetry were performed in women with singleton postterm (287 days' or more gestation) pregnancies. The renal and umbilical artery Doppler resistance index (RI) and end-diastolic velocity were measured. Stepwise logistic regression and the two-tailed t test were used to determine whether the Doppler indices correlated with oligohydramnios (amniotic fluid index less than 5 cm). RESULTS: We studied 147 well-dated, singleton, postterm pregnancies, of which 21 (14.3{\%}) had oligohydramnios. For the study cohort, the mean (±standard deviation) gestational age at Doppler was 41.4 ± 0.45 weeks and at delivery 41.8 ± 0.47 weeks. Stepwise logistic regression using renal and umbilical artery Doppler indices found the renal RI to be the only significant predictor of oligohydramnios: β = -10.4186, P < .05 (odds ratio [95{\%} confidence interval (CI)] = 0, 0.88). The renal artery RI was significantly higher in cases with oligohydramnios (RI: mean (±standard error) = 0.8843 ± 0.11 versus 0.8601 ± 0.05, P ≤ 0.05). A renal artery Doppler end-diastolic velocity below the mean for gestation significantly increased the risk of oligohydramnios: relative risk (95{\%} CI), 1.5 (1.1, 2.0). CONCLUSION: Renal artery Doppler was more predictive of oligohydramnios than the umbilical RI. The reduced renal artery end-diastolic velocity suggests that increased arterial impedance is an important factor in the development of oligohydramnios in prolonged pregnancies.",
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AU - Mari, Giancarlo

AU - Bahado-Singh, R. O.

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N2 - OBJECTIVE: To investigate the etiology of oligohydramnios in postterm pregnancy using Doppler velocimetry. METHODS: Renal and umbilical artery Doppler velocimetry were performed in women with singleton postterm (287 days' or more gestation) pregnancies. The renal and umbilical artery Doppler resistance index (RI) and end-diastolic velocity were measured. Stepwise logistic regression and the two-tailed t test were used to determine whether the Doppler indices correlated with oligohydramnios (amniotic fluid index less than 5 cm). RESULTS: We studied 147 well-dated, singleton, postterm pregnancies, of which 21 (14.3%) had oligohydramnios. For the study cohort, the mean (±standard deviation) gestational age at Doppler was 41.4 ± 0.45 weeks and at delivery 41.8 ± 0.47 weeks. Stepwise logistic regression using renal and umbilical artery Doppler indices found the renal RI to be the only significant predictor of oligohydramnios: β = -10.4186, P < .05 (odds ratio [95% confidence interval (CI)] = 0, 0.88). The renal artery RI was significantly higher in cases with oligohydramnios (RI: mean (±standard error) = 0.8843 ± 0.11 versus 0.8601 ± 0.05, P ≤ 0.05). A renal artery Doppler end-diastolic velocity below the mean for gestation significantly increased the risk of oligohydramnios: relative risk (95% CI), 1.5 (1.1, 2.0). CONCLUSION: Renal artery Doppler was more predictive of oligohydramnios than the umbilical RI. The reduced renal artery end-diastolic velocity suggests that increased arterial impedance is an important factor in the development of oligohydramnios in prolonged pregnancies.

AB - OBJECTIVE: To investigate the etiology of oligohydramnios in postterm pregnancy using Doppler velocimetry. METHODS: Renal and umbilical artery Doppler velocimetry were performed in women with singleton postterm (287 days' or more gestation) pregnancies. The renal and umbilical artery Doppler resistance index (RI) and end-diastolic velocity were measured. Stepwise logistic regression and the two-tailed t test were used to determine whether the Doppler indices correlated with oligohydramnios (amniotic fluid index less than 5 cm). RESULTS: We studied 147 well-dated, singleton, postterm pregnancies, of which 21 (14.3%) had oligohydramnios. For the study cohort, the mean (±standard deviation) gestational age at Doppler was 41.4 ± 0.45 weeks and at delivery 41.8 ± 0.47 weeks. Stepwise logistic regression using renal and umbilical artery Doppler indices found the renal RI to be the only significant predictor of oligohydramnios: β = -10.4186, P < .05 (odds ratio [95% confidence interval (CI)] = 0, 0.88). The renal artery RI was significantly higher in cases with oligohydramnios (RI: mean (±standard error) = 0.8843 ± 0.11 versus 0.8601 ± 0.05, P ≤ 0.05). A renal artery Doppler end-diastolic velocity below the mean for gestation significantly increased the risk of oligohydramnios: relative risk (95% CI), 1.5 (1.1, 2.0). CONCLUSION: Renal artery Doppler was more predictive of oligohydramnios than the umbilical RI. The reduced renal artery end-diastolic velocity suggests that increased arterial impedance is an important factor in the development of oligohydramnios in prolonged pregnancies.

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