Renal Autotransplantation

An alternative to standard renal revascularization procedures

G. A. Sicard, L. I. Valentin, Michael Freeman, B. T. Allen, C. B. Anderson

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

From January 1978 through December 1987, 22 patients underwent 23 renal autotransplantation procedures for the treatment of renovascular hypertension through the retroperitoneal approach. The causes of the renal artery stenosis were as follows: atherosclerosis (15), fibromuscular dysplasia (6), and Takayasu's (1). Indications for renal autotransplantation were as follow: disease extending into the renal artery branches (10), stenosis of multiple renal arteries (6), atherosclerotic aorta in high-risk patients (4), and stenosis of renal artery in children (2). The mean preoperative blood pressure of 205 ± 6/109 ± 3 mm Hg decreased signficantly to 139 ± 4/77 ± 2 mm Hg (p<0.001). The serum creatinine decreased significantly from a mean preoperative level of 2.2 ± 0.8 mg/dl to a mean postoperative level of 1.4 ± 0.4 mg/dl (p<0.05). Eleven patients with preoperative renal dysfunction had a significant decrease in the serum creatinine from a mean preoperative level of 3.4 ± 0.3 mg/dl to a mean postoperative level of 0.19 ± 0.2 mg/dl (p<0.001). One operative death occurred as a result of myocardial infarction. There were three postoperative complications, none of which affected the ultimate results in blood pressure or renal function. This experience demonstrates that in selected patients, renal autotransplantation is an excellent alternative in the surgical treatment of renovascular hypertension.

Original languageEnglish (US)
Pages (from-to)624-630
Number of pages7
JournalSurgery
Volume104
Issue number4
StatePublished - Jan 1 1988
Externally publishedYes

Fingerprint

Autologous Transplantation
Renal Artery Obstruction
Kidney
Renovascular Hypertension
Creatinine
Fibromuscular Dysplasia
Blood Pressure
Renal Artery
Serum
Aorta
Atherosclerosis
Myocardial Infarction
Therapeutics

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Sicard, G. A., Valentin, L. I., Freeman, M., Allen, B. T., & Anderson, C. B. (1988). Renal Autotransplantation: An alternative to standard renal revascularization procedures. Surgery, 104(4), 624-630.

Renal Autotransplantation : An alternative to standard renal revascularization procedures. / Sicard, G. A.; Valentin, L. I.; Freeman, Michael; Allen, B. T.; Anderson, C. B.

In: Surgery, Vol. 104, No. 4, 01.01.1988, p. 624-630.

Research output: Contribution to journalArticle

Sicard, GA, Valentin, LI, Freeman, M, Allen, BT & Anderson, CB 1988, 'Renal Autotransplantation: An alternative to standard renal revascularization procedures', Surgery, vol. 104, no. 4, pp. 624-630.
Sicard GA, Valentin LI, Freeman M, Allen BT, Anderson CB. Renal Autotransplantation: An alternative to standard renal revascularization procedures. Surgery. 1988 Jan 1;104(4):624-630.
Sicard, G. A. ; Valentin, L. I. ; Freeman, Michael ; Allen, B. T. ; Anderson, C. B. / Renal Autotransplantation : An alternative to standard renal revascularization procedures. In: Surgery. 1988 ; Vol. 104, No. 4. pp. 624-630.
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