Renormalization of regional brain blood flow during prolonged mild hypoxic exposure in rats

Kui Xu, Michelle Puchowicz, Joseph C. LaManna

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

In this study, we measured regional brain blood flow (BF) in rats during hypoxic exposure. Our data show the hypoxia-induced brain blood flow increase returned to baseline within 1 week as blood hemoglobin increased. Because this return to baseline occurred before capillary angiogenesis, this result suggests that the mechanism for brain blood flow renormalization during prolonged hypoxia exposure is more likely related to the increased systemic arterial oxygen carrying capacity than to local tissue hypoxia that persists for at least 2 weeks.

Original languageEnglish (US)
Pages (from-to)188-191
Number of pages4
JournalBrain Research
Volume1027
Issue number1-2
DOIs
StatePublished - Nov 19 2004
Externally publishedYes

Fingerprint

Regional Blood Flow
Brain
Brain Hypoxia
Conservation of Natural Resources
Hemoglobins
Oxygen
Hypoxia

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Developmental Biology
  • Clinical Neurology

Cite this

Renormalization of regional brain blood flow during prolonged mild hypoxic exposure in rats. / Xu, Kui; Puchowicz, Michelle; LaManna, Joseph C.

In: Brain Research, Vol. 1027, No. 1-2, 19.11.2004, p. 188-191.

Research output: Contribution to journalArticle

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