Reorganization of verbal memory function in early onset left temporal lobe epilepsy

Michael Seidenberg, Bruce P. Hermann, Jen Schoenfeld, Keith Davies, Allen Wyler, F Dohan

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The purpose of this investigation was to examine the issue of reorganization of verbal memory function following early insult to the left mesial temporal region. It was hypothesized that reorganization of memory function was most likely to occur in those patients with an early age of seizure onset who have a more limited degree of extra-hippocampal neuropathology. Fifty-four patients with epilepsy of unequivocal left temporal lobe origin were classified into four groups on the basis of the presence/absence of hippocampal sclerosis and degree of postoperative seizure relief. Measures of verbal learning and memory as well as nonmemory measures were administered both before and 6 to 8 months after anterior temporal lobectomy. Findings were consistent with the reorganization proposal. The clinical and theoretical significance of the findings are discussed.

Original languageEnglish (US)
Pages (from-to)132-148
Number of pages17
JournalBrain and Cognition
Volume35
Issue number1
DOIs
StatePublished - Jan 1 1997

Fingerprint

Temporal Lobe Epilepsy
Temporal Lobe
Seizures
Anterior Temporal Lobectomy
Verbal Learning
Sclerosis
Age of Onset
Epilepsy
Onset
Verbal Memory
Reorganization

All Science Journal Classification (ASJC) codes

  • Neuropsychology and Physiological Psychology
  • Experimental and Cognitive Psychology
  • Developmental and Educational Psychology
  • Arts and Humanities (miscellaneous)
  • Cognitive Neuroscience

Cite this

Reorganization of verbal memory function in early onset left temporal lobe epilepsy. / Seidenberg, Michael; Hermann, Bruce P.; Schoenfeld, Jen; Davies, Keith; Wyler, Allen; Dohan, F.

In: Brain and Cognition, Vol. 35, No. 1, 01.01.1997, p. 132-148.

Research output: Contribution to journalArticle

Seidenberg, M, Hermann, BP, Schoenfeld, J, Davies, K, Wyler, A & Dohan, F 1997, 'Reorganization of verbal memory function in early onset left temporal lobe epilepsy', Brain and Cognition, vol. 35, no. 1, pp. 132-148. https://doi.org/10.1006/brcg.1997.0931
Seidenberg, Michael ; Hermann, Bruce P. ; Schoenfeld, Jen ; Davies, Keith ; Wyler, Allen ; Dohan, F. / Reorganization of verbal memory function in early onset left temporal lobe epilepsy. In: Brain and Cognition. 1997 ; Vol. 35, No. 1. pp. 132-148.
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